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Eniluracil
go.drugbank.com/drugs/DB03516InvestigationalEniluracil could improve 5-FU by increasing its effectiveness, reducing its side effects and/or making it orally available.
PPI-2458
go.drugbank.com/drugs/DB05864InvestigationalPPI-2458 represents a potentially new and important addition to the growing list of therapeutics aimed at specific molecular oncology targets.
Chlorotoxin I-131
go.drugbank.com/drugs/DB05462InvestigationalIt is a synthetic version of a neurotoxin isolated from the venom of the Giant Yellow Israeli scorpion Leiurus quinquestriatus.
Synonyms: I(131)-TM-601 (chlorotoxin)ZYCOV-D
go.drugbank.com/drugs/DB15892ExperimentalOnce the plasmid DNA is introduced into host cells and the viral protein is translated, it elicits a strong immune response, stimulating the humoral and cellular components of the immune system[L16503]
BBV152
go.drugbank.com/drugs/DB15847InvestigationalAnimal studies in mice, rats, and rabbits reported BBV152 immunogenicity at two separate antigen concentrations with both types of adjuvants.
TRC093
go.drugbank.com/drugs/DB06356InvestigationalTRC093 is a recombinant humanized IgG1k monoclonal antibody.
Smilagenin
go.drugbank.com/drugs/DB05450InvestigationalPre-clinical work with smilagenin showed it to be neuroprotective against betya-amyloid and glutamate damage which contributes to Alzheimer's disease and reverses the changes in the area of the brain involved
UB-612
go.drugbank.com/drugs/DB16444InvestigationalIt was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658].
Anti-SARS-CoV-2 REGN-COV2
go.drugbank.com/drugs/DB15691InvestigationalRegeneron's clinical trial will study the effects of this drug on hospitalized COVID-19 patients, symptomatic COVID-19 patients (non-hospitalized), and uninfected individuals at high-risk of infection,
PI-0824
go.drugbank.com/drugs/DB05516InvestigationalIt is hoped that use of PI-0824 will reduce or potentially eliminate the need for high dose steroids and drugs that suppress the immune system.