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Displaying results 6071 - 6080 of 10000 in total
  1. Drug

    Fanregratinib

    go.drugbank.com/drugs/DB21688
    Experimental

    The usage of the INN stem '-gratinib' in the name indicates that Fanregratinib is a fibroblast growth factor receptor (FGFR) inhibitor. Fanregratinib has a monoisotopic molecular weight of 508.24 Da.

  2. Drug

    Ilantimod

    go.drugbank.com/drugs/DB21742
    Experimental

    The usage of the INN stem '-imod' in the name indicates that Ilantimod is a immunomodulator, both stimulant/suppressive and stimulant. Ilantimod has a monoisotopic molecular weight of 387.11 Da.

  3. Drug

    10-hydroxycamptothecin

    go.drugbank.com/drugs/DB12385
    Experimental

    10-hydroxycamptothecin is under investigation in clinical trial NCT00956787 (Study of AR-67 (DB-67) in Myelodysplastic Syndrome (MDS)).

  4. Drug

    Ketodarolutamide

    go.drugbank.com/drugs/DB15647
    Experimental

    Ketodarolutamide, a nonsteroidal antiandrogen (NSAA), is the major active metabolite of [darolutamide].

    Categories: Antiandrogens, non-steroidal
  5. Drug

    Irampanel

    go.drugbank.com/drugs/DB21123
    Investigational

    Irampanel has a monoisotopic molecular weight of 309.15 Da. … Irampanel is under investigation in clinical trial NCT02222961 (Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers).

  6. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    [L6676] Through this mechanism of action, axitinib blocks angiogenesis, tumour growth and metastases. … It is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative.

    Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
  7. Drug

    Ridogrel

    go.drugbank.com/drugs/DB01207
    Experimental

    However, there currently are no clinical indications for preferential use of ridogrel over aspirin. … Ridogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction.

  8. Drug

    Bifemelane

    go.drugbank.com/drugs/DB13550
    Experimental

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  9. Drug

    RTP-801i

    go.drugbank.com/drugs/DB06048
    Investigational

    The proposed primary indication for RTP-801i is the treatment of patients with neovascular (wet) Age-related Macular Degeneration (AMD or ARMD). … RTP-801i is an siRNA drug candidate designed to inhibit the expression of the hypoxia-inducible gene RTP801.

  10. Drug

    Mivebresib

    go.drugbank.com/drugs/DB21300
    Investigational

    Mivebresib has a monoisotopic molecular weight of 459.11 Da. … The usage of the INN stem '-bresib' in the name indicates that Mivebresib is a inhibitor of the bromodomain and extra-terminal motif (BET) family of bromodomain (BRD) protein, antineoplastic.