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Ulixertinib
go.drugbank.com/drugs/DB13930InvestigationalUlixertinib is a a novel, reversible, ATP-competitive ERK1/2 inhibitor with high potency and ERK1/2 selectivity [A31474]. … It is currently in clinical trials for the treatment of a wide range of tumors.
Categories: Heterocyclic Compounds, 1-RingVoretigene neparvovec
go.drugbank.com/drugs/DB13932ApprovedInvestigationalIt is not pathogenic and it causes a very mild immune response. … Voretigene Neparvovec-rzyl (VN-rzyl) is an adeno-associated virus vector-based gene therapy.[L1094] An adeno-associated virus is a small virus that infects humans and other primates.
Vosilasarm
go.drugbank.com/drugs/DB13939InvestigationalRAD140 is an investigational selective androgen receptor modulator (SARM) for the treatment of conditions such as muscle wasting and breast cancer.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 2-Chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrileTestosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigationalTestosterone undecanoate is the ester prodrug of [testosterone] and has a mid-chain fatty acid at the carbon 17β position. … [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sex characteristics
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: UROMAX® 1000MG/4 ML SOLUCIÓNINYECTABLE, NEBIDO ®Ferric cation
go.drugbank.com/drugs/DB13949ApprovedWithdrawnIron is a transition metal with a symbol Fe and atomic number 26. By mass, it is the most common element on Earth. … Non-haem iron in food is mainly in the ferric state, which is the insoluble form of iron, and must be reduced to the ferrous cation for absorption [T28].
Synonyms: iron(3+)Products: FERIMAX 100 MG/5 ML ORAL SOLUSYON 10 FLAKON, FERRUM HAUSMANN 100 MG/5 ML ORAL ÇÖZELTİ, 20 ADETStanolone acetate
go.drugbank.com/drugs/DB13951ExperimentalStanolone acetate is a synthetic androgen and anabolic steroid and a dihydrotestosterone ester that was never marketed.
Categories: P-glycoprotein substratesEstradiol acetate
go.drugbank.com/drugs/DB13952ApprovedVet approvedEstradiol acetate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … [DB00783] is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A1 SubstratesSynonyms: Estradiol 3-acetate, Estradiol-3-acetateEstradiol dienanthate
go.drugbank.com/drugs/DB13955ApprovedVet approvedWithdrawnEstradiol Dienanthate is a pro-drug ester of [DB00783], a naturally occurring hormone that circulates endogenously within the human body. … Estradiol is commonly produced with an ester side-chain as endogenous estradiol has very low oral bioavailability on its own (2-10%).
Categories: Cytochrome P-450 CYP1A1 Substrates, P-glycoprotein substratesSelisistat
go.drugbank.com/drugs/DB13978InvestigationalSelective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3, HDAC and NADase respecti...
Synonyms: rac-6-Chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamideCategories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 3-Ring