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Displaying results 601 - 610 of 10000 in total
  1. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative … Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.[A253907]

    Products: PEMETREXED DR. REDDY'S, PEMETREXED 500 MG POLVO LIOFILIZADO PARA SOLUCIÓN DE INFUSIÓN.
  2. Drug

    Panax notoginseng root

    go.drugbank.com/drugs/DB14304
    Investigational

    Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Tienchi Ginseng (Constituent of American Ginseng, Asian Ginseng, and Tienchi Ginseng), San QiMixtures: GONGFUTOUTANG Tou Tang Powder No. 3
  3. Drug

    Cabazitaxel

    go.drugbank.com/drugs/DB06772
    ApprovedInvestigational

    It was first approved by the FDA on June 17, 2010.[A260421] It was also approved by the EMA on March 17, 2011 [L47381] and Health Canada on December 17, 2019.[L47376] … [A7056] Due to its low affinity for the P-glycoprotein (P-gp) efflux pump, cabazitaxel can more readily penetrate the blood–brain barrier compared to other taxanes like [paclitaxel] and [docetaxel].

    Products: CABAZITAXEL DR. REDDYS
  4. Drug

    CX-052075

    go.drugbank.com/drugs/DB31655
    Approved

    the SARS-CoV-2 spike protein, allowing for a more targeted immune response and the use of a significantly smaller amount of mRNA per dose. … CX-052075 is a nucleoside-modified messenger RNA (mRNA) encoding the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein of the SARS-CoV-2 Omicron variant sublineage LP.8.1

  5. Drug

    Teriflunomide

    go.drugbank.com/drugs/DB08880
    ApprovedInvestigational

    Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.

    Categories: Analgesics, Non-NarcoticProducts: TERIFLUNOMIDE DR. REDDY'S
  6. Drug

    Remdesivir

    go.drugbank.com/drugs/DB14761
    ApprovedInvestigational

    Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase (RdRp) enzyme complex for genomic replication, which can be inhibited by a class of drugs known as nucleoside analogues. … [A191427, A198810] Remdesivir was confirmed as a non-obligate chain terminator of RdRp from SARS-CoV-2 and the related SARS-CoV and MERS-CoV,[A222398] and has been investigated in multiple COVID-19 clinical

    Categories: SARS-CoV-2 Nucleotide Analog RNA Polymerase Inhibitor
  7. Drug

    Nadroparin

    go.drugbank.com/drugs/DB08813
    ApprovedInvestigationalWithdrawn

    The amplification of the fibrin clotting cascade is stopped once factors Xa and IIa are inactivated. It is derived from porcine sources and has a mean molecular size of 5000 daltons. … Nadroparin halts the coagulation pathway by inhibiting the activation of thrombin (factor IIa) by factor Xa.

    Products: FRAXIPARINE 0.3ML INJ 7,500 IC U AXA, FRAXIPARINE INJECTION 1900 IU AXA/0.2 mL
  8. Drug

    Flurbiprofen

    go.drugbank.com/drugs/DB00712
    ApprovedInvestigational

    Oral formulations of flurbiprofen may be used for the symptomatic treatment of rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. … Flurbiprofen may also be used topically prior to ocular surgery to prevent or reduce intraoperative miosis.

    Mixtures: MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 G, MERDEX DUO %5 + %0.25 TOPIKAL JEL, 30 GCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-Narcotic
  9. Drug

    Ceftriaxone

    go.drugbank.com/drugs/DB01212
    ApprovedInvestigational

    the convenience of daily or twice-daily dosing. … Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus.

    Products: MEDAXONE POWDER FOR SOLUTION FOR INJECTION OR INFUSION 1 G/VIAL, MEDAXONE POWDER FOR SOLUTION FOR INJECTION OR INFUSION 2 G/VIAL
  10. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    [A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809] … [L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described in the literature in 1974.

    Products: Dermovate Ont 0.05%, Alti-clobetasol Propionate Ont 0.05%