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Displaying results 601 - 610 of 9613 in total
  1. Drug

    Fluorometholone

    go.drugbank.com/drugs/DB00324
    ApprovedInvestigational

    A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)

    Mixtures: FLU-SURE T® SUSPENSIÓN OFTÁLMICAProducts: FLUOROPOS GOZ DAMLASI 1MG/ML 5ML, PMS-fluorometholone
  2. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Synonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, -HYDROXY-, (2AR,4S,4AS,6R,9S,11S,12S,12AR,12BS)-6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYCLODECA(3Products: EBETAXEL EBEWE 150MG/25ML ENJEKTABL, ANZATAX 150MG/25ML ENJ. SOL. ICEREN FLAKON, 1 ADET
  3. Drug

    Hydrocortisone acetate

    go.drugbank.com/drugs/DB14539
    ApprovedInvestigationalVet approved

    Mixtures: Anodan-HC 10mg Suppositories, Actinac PwsProducts: Cortiment-10 Sup 10mg, Cortiment-40 Sup 40mg
  4. Drug

    Mosunetuzumab

    go.drugbank.com/drugs/DB15434
    ApprovedInvestigational

    [A249320,A249390] Mosunetuzumab has the potential to circumvent resistance to [rituximab] in patients with follicular lymphoma,[A249320,L42230] and unlike CAR-T therapies such as [axicabtagene ciloleucel … [L42230] It can recognize and bind two different targets simultaneously, CD20 on cancer B-cells and CD3 on T-cells, allowing it to redirect T-cell cytotoxic activity to cancer cells.

    Products: Lunsumio 1mg/ml Concentrate for Solution for Infusion
  5. Drug

    Dopamine

    go.drugbank.com/drugs/DB00988
    ApprovedInvestigational

    It is derived from tyrosine and is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement.

    Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML)Products: Intropin Injection 40mg/ml, DOPMIN 40MG/ML INFUSION CONCENTRATE
  6. Drug

    Zolmitriptan

    go.drugbank.com/drugs/DB00315
    ApprovedInvestigational

    It is currently available in both tablet and nasal spray forms.[L12978] … [A462, L12978] [Sumatriptan] was the first triptan to be developed, but had poor oral bioavailability and lipophilicity.

    Products: PMS-zolmitriptan, PMS-zolmitriptan ODT
  7. Drug

    Vardenafil

    go.drugbank.com/drugs/DB00862
    Approved

    [A258313] The use of vardenafil as a monotherapy for the treatment of pulmonary arterial hypertension has also been evaluated.[A258308] … Although other PDE5 inhibitors such as [sildenafil] and [tadalafil] have been associated with rare cases of acute liver injury, the use of vardenafil has not been linked to hepatotoxic effects.

    Products: LEVITRA 10MG TABLET, LEVITRA 20MG TABLET
  8. Drug

    Glibornuride

    go.drugbank.com/drugs/DB08962
    ApprovedWithdrawn

    Glibornuride is a sulfonylurea-type anti-diabetic drug.

    Products: GLUTRIL 25MG TABLET, 100 ADET, GLUTRIL 25MG TABLET, 50 ADET
  9. Drug

    Alogliptin

    go.drugbank.com/drugs/DB06203
    ApprovedInvestigational

    Chemically, alogliptin is prepared as a benzoate salt and exists predominantly as the R-enantiomer (>99%). It undergoes little or no chiral conversion in vivo to the (S)-enantiomer.

    Mixtures: OSENI FILM COATED TABLET 25MG/ 15MG, OSENI FILM COATED TABLET 25MG/ 30MGProducts: Nesina 25mg Film-Coated Tablet
  10. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … [A36559] Metformin was first approved in Canada in 1972,[A36552] and received subsequent FDA approval in the US in 1995.[L12207]

    Mixtures: XIGDUO XR TABLETS 10MG/500MG, XIGDUO XR TABLETS 10MG/1000MGProducts: FORMET TABLET 250mg, SW Metformin 250mg Tablet