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Metribolone

It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.

Olinciguat

, Olinciguat (IW-1701), in Healthy Volunteers). … Olinciguat is under investigation in clinical trial NCT03892499 (A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of the Soluble Guanylate Cyclase Stimulator

Daledalin

It has no effects on the reuptake of serotonin or dopamine, and no antihistamine or anticholinergic properties. It was in trials for depression in the 1970s but never marketed.

PB127

Morus alba root bark

Morus alba root bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Magnolia kobus flowering top

Magnolia kobus flowering top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

Zanthoxylum clava-herculis bark

Zanthoxylum clava-herculis bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

VM4-037

VM4-037 is under investigation in clinical trial NCT00884520 (An Exploratory, Open Label, Multi-Center, Non-Randomized Study of [F-18]VM4-037).

Glafenine

An anthranilic acid derivative with analgesic properties used for the relief of all types of pain. Glafenine is withdrawn from the American market.

RGN6024

Reglagene announced FDA orphan drug designation for glioblastoma in 2024. RGN6024 remains investigational and is not an approved drug. … cells, and suppresses tumor growth in glioblastoma xenograft models.