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Displaying results 6091 - 6100 of 10000 in total
  1. Drug

    ARC183

    go.drugbank.com/drugs/DB05124
    Experimental

    ARC183 is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity … resolution of anticoagulation or that require reversal of anticoagulation shortly after the procedure is completed.

  2. Drug

    Sodium tripolyphosphate

    go.drugbank.com/drugs/DB11493
    InvestigationalVet approved

    It is used as a component of a wide range domestic and industrial products, particularly detergents. … Sodium tripolyphosphate is an inorganic compound with formula Na5P3O10 and the sodium salt of the polyphosphate penta-anion.

  3. Drug

    Trestolone acetate

    go.drugbank.com/drugs/DB13958
    Experimental

    Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. … It is an androgen ester – specifically, the C17 acetate ester of [DB05830].

    Synonyms: 17β-Hydroxy-7α-methylestr-4-en-3-one acetate, 17beta-Hydroxy-7alpha-methylestr-4-en-3-one acetate
  4. Drug

    CER-001

    go.drugbank.com/drugs/DB18538
    Investigational

    CER-001 is a negatively charged lipoprotein particle comprising human recombinant apolipoprotein A-I and two phospholipids: sphingomyelin and dipalmitoylphosphatidylglycerol. … [L48290] It is under investigation for the treatment of lecithin-cholesterol acyltransferase (LCAT) deficiencies.

    Categories: Apolipoproteins ASynonyms: Recombinant human apolipoprotein A-I/phospholipid complexes
  5. Drug

    Lavamilast

    go.drugbank.com/drugs/DB19767
    Experimental

    Lavamilast is a small molecule drug. The usage of the INN stem '-milast' in the name indicates that Lavamilast is a Phosphodiesterase-4 (PDE4) inhibitor. … Lavamilast has a monoisotopic molecular weight of 520.16 Da.

  6. Drug

    MP4

    go.drugbank.com/drugs/DB05313
    Investigational

    MP4 is a hemoglobin-based oxygen carrier designed to serve as an alternative for blood transfusions. … It is free of harmful vasoactivity and provides targeted oxygen delivery to tissues at risk of oxygen deprivation.

  7. Drug

    Bertilimumab

    go.drugbank.com/drugs/DB05429
    Investigational

    Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development. … It is developed by MedImmune for the treatment of Allergic Rhinitis.

    Synonyms: IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CAT-213 .KAPPA.-CHAIN, DIMER
  8. Drug

    PRO-1562

    go.drugbank.com/drugs/DB33979
    Experimental

    PRO-1562 is a small molecule drug. … PRO-1562 is under investigation in clinical trial NCT07826689 (A Phase 1/2a Study of Oral PRO-1562 in Healthy Subjects and Patients With Relapsing Multiple Sclerosis).

  9. Drug

    Itacnosertib

    go.drugbank.com/drugs/DB21463
    Experimental

    Itacnosertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Itacnosertib is a serine/threonine kinase inhibitor. … Itacnosertib has a monoisotopic molecular weight of 468.24 Da.

  10. Drug

    Cotosudil

    go.drugbank.com/drugs/DB21482
    Experimental

    Cotosudil is a small molecule drug. The usage of the INN stem '-sudil' in the name indicates that Cotosudil is a Rho protein kinase inhibitor. … Cotosudil has a monoisotopic molecular weight of 319.14 Da.