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Displaying results 6101 - 6110 of 10000 in total
  1. Drug

    Sarilumab

    go.drugbank.com/drugs/DB11767
    ApprovedInvestigational

    Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling … cascades of IL-6.

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  2. Drug

    Cenderitide

    go.drugbank.com/drugs/DB11777
    Investigational

    Cenderitide is under investigation for the treatment of ST Elevation (STEMI) Myocardial Infarction of Anterior Wall.

  3. Drug

    Tanzisertib

    go.drugbank.com/drugs/DB11798
    Investigational

    Tanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.

    Synonyms: 4-[[9-(3S)-tetrahydro-3-furanyl]-8-[(2,4,6-trifluorophenyl)amino]-9H-purin-2-yl]amino]-trans-cyclohexanol, CYCLOHEXANOL, 4-((9-((3S)-TETRAHYDRO-3-FURANYL)-8-((2,4,6-TRIFLUOROPHENYL)AMINO)-9H-PURIN-2-YL)AMINO)-, TRANS-Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Artefenomel

    go.drugbank.com/drugs/DB11809
    Investigational

    Artefenomel has been investigated for the treatment of Malaria.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  5. Drug

    Baricitinib

    go.drugbank.com/drugs/DB11817
    ApprovedInvestigational

    Baricitinib is a Janus kinase (JAK) inhibitor. JAKs are tyrosine protein kinases that play an important role in pro-inflammatory signaling pathways. … Overactive JAKs have been implicated in autoimmune disorders, such as rheumatoid arthritis.

    Categories: MATE 2 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: UNAMİTY 4 MG FİLM KAPLI TABLET, 7 ADET, UNAMİTY 2 MG FİLM KAPLI TABLET, 7 ADET
  6. Drug

    Retosiban

    go.drugbank.com/drugs/DB11818
    Investigational

    Retosiban has been used in trials studying the treatment of Premature Labor and Obstetric Labour, Premature.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    ASP-4058

    go.drugbank.com/drugs/DB11819
    Investigational

    ASP4058 has been used in trials studying Food Effect of ASP4058 and Pharmacokinetics of ASP4058.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Danegaptide

    go.drugbank.com/drugs/DB11821
    Investigational

    Danegaptide has been investigated for the treatment of Focus of Study is STEMI.

  9. Drug

    Pritelivir

    go.drugbank.com/drugs/DB11844
    Investigational

    Pritelivir has been used in trials studying the prevention of HSV-2 and Genital Herpes.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  10. Drug

    Revefenacin

    go.drugbank.com/drugs/DB11855
    ApprovedInvestigational

    The LAMA group falls into a parent category known as long-acting inhaled bronchodilators and this type of agents are recommended as a maintenance therapy for chronic obstructive pulmonary disease (COPD … Revefenacin is a novel biphenyl carbamate tertiary amine agent that belongs to the family of the long-acting muscarinic antagonists (LAMA).

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substrates