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Displaying results 6111 - 6120 of 10000 in total
  1. Drug

    ACA 125

    go.drugbank.com/drugs/DB05489
    Investigational

    Antiidiotypic antibodies bearing the internal image of an antigen expressed on the surface of the tumor are suited to this approach. … This new concept of oncological immunotherapy consists of an attempt to trigger the immune system of the host to respond against tumor cells.

  2. Drug

    Mosapride

    go.drugbank.com/drugs/DB11675
    Investigational

    Mosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). … Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  3. Drug

    Benactyzine

    go.drugbank.com/drugs/DB09023
    ApprovedWithdrawn

    Benactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. … Benactyzine is no longer widely used in medicine, although it is still a useful drug for scientific research. It does not possess any antihistamine properties.

  4. Drug

    Alofanib

    go.drugbank.com/drugs/DB20918
    Investigational

    Alofanib is under investigation in clinical trial NCT04071184 (Study of Alofanib in Patients With Metastatic Gastric Cancer). Alofanib has a monoisotopic molecular weight of 413.07 Da. … The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor.

  5. Drug

    Glibornuride

    go.drugbank.com/drugs/DB08962
    ApprovedWithdrawn

    Glibornuride is a sulfonylurea-type anti-diabetic drug.

    Categories: Drugs Used in Diabetes
  6. Drug

    Opnurasib

    go.drugbank.com/drugs/DB21583
    Investigational

    Opnurasib has a monoisotopic molecular weight of 525.2 Da. … Opnurasib is under investigation in clinical trial NCT05132075 (Study of JDQ443 in Comparison With Docetaxel in Participants With Locally Advanced or Metastatic KRAS G12C Mutant Non-small Cell Lung Cancer

  7. Drug

    Quinidine barbiturate

    go.drugbank.com/drugs/DB01346
    Approved

    The administration of quinidine derivatives helps to observe various skin and mucosal reactions. … A papulopurpuric eruption in a patient (without thrombopenia) can be developed who is taking quinidine phenylethyl barbiturate intermittently and at reintroduction.(PMID: 9739909)

  8. Drug

    Amuvatinib

    go.drugbank.com/drugs/DB12742
    Investigational

    Amuvatinib has been used in trials studying the treatment of Solid Tumors and Small Cell Lung Carcinoma. … Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA repair in cancer cells.

    Synonyms: 1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl-, 4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-Carbothioamide
  9. Drug

    Lotrafiban

    go.drugbank.com/drugs/DB20872
    Experimental

    Lotrafiban has a monoisotopic molecular weight of 428.24 Da. … The usage of the INN stem '-fiban' in the name indicates that Lotrafiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).

  10. Drug

    Lamifiban

    go.drugbank.com/drugs/DB20451
    Experimental

    Lamifiban has a monoisotopic molecular weight of 468.2 Da. … The usage of the INN stem '-fiban' in the name indicates that Lamifiban is a fibrinogen receptor antagonist (glycoprotein IIb/IIIa receptor antagonist).