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Displaying results 6121 - 6130 of 10000 in total
  1. Drug

    RUTI® Vaccine

    go.drugbank.com/drugs/DB15853
    Investigational

    Sponsored by Fundació Institut Germans Trias i Pujol, the RUTI® Vaccine is being tested for prevention of COVID-19 infection in a controlled trial with 315 healthcare worker participants (NCT04453488). … Much like the BCG vaccine, the RUTI® vaccine is also being tested as a prophylactic for SARS-CoV2.

  2. Drug

    Benzylparaben

    go.drugbank.com/drugs/DB14176
    Approved

    Benzylparaben is used in allergenic testing.

  3. Drug

    EHT899

    go.drugbank.com/drugs/DB05108
    Experimental

    It also apparently enhances a secondary immune response to clear the viral infection, resulting in reduction in liver damage and decrease in viral load. … EHT899 is a proprietary formulation of an HBV viral protein designed to eliminate the undesirable immune response elicited by the HBV infection.

  4. Drug

    Vociprotafib

    go.drugbank.com/drugs/DB21559
    Investigational

    Vociprotafib is under investigation in clinical trial NCT05054725 (Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies). … Vociprotafib is a small molecule drug. The usage of the INN stem '-protafib' in the name indicates that Vociprotafib is a human protein tyrosine phosphatase (HPTP) inhibitor.

  5. Drug

    Afimkibart

    go.drugbank.com/drugs/DB18718
    Investigational

    It is being investigated for ulcerative colitis. … RVT-3101 is a fully human monoclonal antibody targeting vascular endothelial growth inhibitor, also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15.

  6. Drug

    CR002

    go.drugbank.com/drugs/DB05139
    Investigational

    CR002 is a novel investigational fully human monoclonal antibody that blocks the activity of excess platelet-derived growth factor-D (PDGF-D), a target shown to play a role in kidney inflammation. … This is a novel therapeutic approach to treat kidney inflammation.

  7. Drug

    Vadimezan

    go.drugbank.com/drugs/DB06235
    Investigational

  8. Drug

    AAV1-FS344

    go.drugbank.com/drugs/DB17855
    Investigational

    AAV1-FS344 is an investigational gene therapy developed by Milo Biotechnology to deliver follistatin, a potent myostatin inhibitor. … It is being investigated for the treatment of Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, and inclusion body myositis.[L46742, L46747, L46752]

  9. Drug

    R343

    go.drugbank.com/drugs/DB06316
    Investigational

    R343, was investigated in clinical trial NCT01591044 to evaluate its safety and efficacy in patients with mild to moderate asthma.

    Synonyms: 2- {3- [4-(2,2-Difluoro-3 -oxo-3,4-dihydro-2H-benzo [1,4] oxazin-6-ylamino)5-fluoro-pyrimidin-2-ylamino]phenoxy}N-methyl-acetamide
  10. Drug

    Cannabichromene

    go.drugbank.com/drugs/DB14735
    Investigational

    A natural product found in Cannabis sativa and Helichrysum species.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates