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Displaying results 6151 - 6160 of 10000 in total
  1. Drug

    Ifenprodil

    go.drugbank.com/drugs/DB08954
    ApprovedInvestigationalWithdrawn

    Binding at the LBD of the agonists glycine (or D-serine) to the GluN1 subunits and of glutamate to the GluN2 subunits is a regulatory mechanism for channel activation. … [A196128] Ifenprodil is being investigated for its potential utility in treating COVID-19 in an ongoing phase 2b/3 clinical trial (NCT04382924).[L16343]

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Medetomidine

    go.drugbank.com/drugs/DB11428
    ExperimentalVet approved

    Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. … The marketed product is a racemic mixture of two stereoisomers from which dexmedetomidine is the main active isomer.

    Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsSynonyms: (±)-4-(α,2,3-trimethylbenzyl)imidazole
  3. Drug

    Ribuvaptan

    go.drugbank.com/drugs/DB20059
    Experimental

    Ribuvaptan is a small molecule drug. The usage of the INN stem '-vaptan' in the name indicates that Ribuvaptan is a vasopressin receptor antagonist. … Ribuvaptan has a monoisotopic molecular weight of 595.11 Da.

  4. Drug

    Fasobegron

    go.drugbank.com/drugs/DB20200
    Experimental

    Fasobegron is a small molecule drug. The usage of the INN stem '-begron' in the name indicates that Fasobegron is a β3​ adrenoreceptor agonists. … Fasobegron has a monoisotopic molecular weight of 425.14 Da.

  5. Drug

    Tigapotide

    go.drugbank.com/drugs/DB04985
    Investigational

    Tigapotide is a synthetic 15-mer peptide that is derived from the natural sequence of amino acids of the prostate secretory protein (PSP94), one of three predominant proteins found in human seminal fluid

  6. Drug

    Vibriolysin

    go.drugbank.com/drugs/DB05135
    Experimental

    Vibriolysin is a proteolytic enzyme secreted by the marine microorganism Vibrio proteolyticus. … It is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds.

  7. Drug

    Ruclosporin

    go.drugbank.com/drugs/DB21199
    Experimental

    Ruclosporin is a small molecule drug. The usage of the INN stem '-(clo)sporin' in the name indicates that Ruclosporin is a cyclosporine derivative. … Ruclosporin has a monoisotopic molecular weight of 1330.92 Da.

  8. Drug

    Filapixant

    go.drugbank.com/drugs/DB21467
    Experimental

    Filapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. … Filapixant has a monoisotopic molecular weight of 521.17 Da.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  9. Drug

    Teplinovivint

    go.drugbank.com/drugs/DB21475
    Experimental

    Teplinovivint is a small molecule drug. The usage of the INN stem '-vivint' in the name indicates that Teplinovivint is a Wnt signaling inhibitor. … Teplinovivint has a monoisotopic molecular weight of 442.21 Da.

  10. Drug

    Ipivivint

    go.drugbank.com/drugs/DB21479
    Experimental

    Ipivivint is a small molecule drug. The usage of the INN stem '-vivint' in the name indicates that Ipivivint is a Wnt signaling inhibitor. Ipivivint has a monoisotopic molecular weight of 464.19 Da.