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Guanosine
go.drugbank.com/drugs/DB02857InvestigationalGuanosine is a nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond. … Guanosine can be phosphorylated to become GMP (guanosine monophosphate), cGMP (cyclic guanosine monophosphate), GDP (guanosine diphosphate) and GTP (guanosine triphosphate) which are factors in signal
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-amino-1,9-dihydro-9-β-D-ribofuranosyl-6H-purin-6-one, 2(3H)-imino-9-β-D-ribofuranosyl-9H-purin-6(1H)-oneLotiglipron
go.drugbank.com/drugs/DB21631InvestigationalLotiglipron is a small molecule drug. The usage of the INN stem '-glipron' in the name indicates that Lotiglipron is a glucagon-like peptide 1 receptor (GLPIR) agonist. … Lotiglipron is under investigation in clinical trial NCT05579977 (Trial to Learn About the Study Medicine (PF-07081532) and Rybelsus in People With Type 2 Diabetes and Separately PF-07081532 in People
NTx-265
go.drugbank.com/drugs/DB05649InvestigationalNTx-265 is a combination of two currently marketed large molecules designed to stimulate the growth and differentiation of neural stem cells in adults who have suffered a stroke – the second leading cause … It is also investigating use of the compound for neurodegenerative disorders, such as Huntington’s disease and Alzheimer’s disease.
Nevadistinel
go.drugbank.com/drugs/DB21632InvestigationalNevadistinel is a small molecule drug. The usage of the INN stem '-stinel' in the name indicates that Nevadistinel is a N-methyl-D-aspartate (NMDA) receptor co-agonist. … Nevadistinel is under investigation in clinical trial NCT04148391 (NYX-458 in Subjects With Mild Cognitive Impairment or Mild Dementia Due to Parkinson's Disease or Lewy Body Dementia (Cognition, Memory
SYNB1891
go.drugbank.com/drugs/DB17541InvestigationalSYNB1891 is a live, modified strain of the probiotic _Escherichia coli_ Nissle engineered to produce cyclic di-AMP (CDA), a stimulator of the STING (STimulator of INterferon Genes) pathway. … [A256733] SYNB1891 is under investigation in clinical trial NCT04167137 (Safety and Tolerability of SYNB1891 Injection Alone or in Combination With Atezolizumab in Adult Subjects).
Clomethiazole
go.drugbank.com/drugs/DB06470InvestigationalIt is also used for the management of agitation, restlessness, short-term insomnia and Parkinson's disease in the elderly. … It is a drug which is structurally related to thiamine (vitamin B1) but acts like a sedative, hypnotic, muscle relaxant and anticonvulsant.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingInarigivir
go.drugbank.com/drugs/DB15062InvestigationalInarigivir is under investigation in clinical trial NCT03434353 (Study to Evaluate the Antiviral Activity of Inarigivir (GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis … B (CHB)).
Stearic acid
go.drugbank.com/drugs/DB03193ApprovedStearic acid (IUPAC systematic name: octadecanoic acid) is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is a waxy solid.
Mixtures: Huile D'onagre Vitamin E, O Hui Veil Fit Dual Foundation 20Synonyms: C18:0, n-octadecanoic acidAZD-4017
go.drugbank.com/drugs/DB14875InvestigationalAZD-4017 is under investigation in clinical trial NCT01173471 (A Phase IIa Study to Assess the Tolerability, Safety, and Efficacy of AZD4017 for Raised Intra-ocular Pressure).
Categories: Heterocyclic Compounds, 1-Ring, 11-beta-Hydroxysteroid Dehydrogenase Type 1, antagonists & inhibitorsOrdesekimab
go.drugbank.com/drugs/DB16649InvestigationalOrdesekimab is under investigation in clinical trial NCT02633020 (Study to Evaluate the Efficacy and Safety of AMG 714 in Adult Patients With Type II Refractory Celiac Disease).