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Nalfurafine
go.drugbank.com/drugs/DB13471InvestigationalCategories: Heterocyclic Compounds with 4 or More RingsICA-105665
go.drugbank.com/drugs/DB06089InvestigationalIt is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy. … In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain.
Aftobetin
go.drugbank.com/drugs/DB20425InvestigationalAftobetin has a monoisotopic molecular weight of 452.23 Da. … Aftobetin is under investigation in clinical trial NCT02928211 (Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations).
Riselcaftor
go.drugbank.com/drugs/DB21685ExperimentalRiselcaftor has a monoisotopic molecular weight of 516.17 Da. … The usage of the INN stem '-caftor' in the name indicates that Riselcaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier.
Arbekacin
go.drugbank.com/drugs/DB06696InvestigationalAn semisynthetic aminoglycoside antibiotic. Often used for treatment of multi-resistant bacterial infection such as methicillin-resistant _Staphylococcus aureus_ (MRSA).
Vabametkib
go.drugbank.com/drugs/DB21629InvestigationalVabametkib has a monoisotopic molecular weight of 566.3 Da. … Vabametkib is under investigation in clinical trial NCT05541822 (To Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetic Profile of ABN401 in Patients With Advanced Solid Tumors Harboring c-MET
Raclopride
go.drugbank.com/drugs/DB12518InvestigationalRaclopride has been used in trials studying Parkinson Disease.
Categories: Dopamine D2 Receptor AntagonistsBisphosphocin Nu-3
go.drugbank.com/drugs/DB16015InvestigationalBisphosphocin Nu-3 is under investigation in clinical trial NCT02737722 (Topically Applied Bisphosphocin Nu-3 on Infected Diabetic Ulcers of Subjects With Type I or II Diabetes Mellitus).
Synonyms: Nu-3, Bisphosphocin Nu-3Ondelopran
go.drugbank.com/drugs/DB12585InvestigationalOndelopran has been used in trials studying the treatment of Alcohol Dependence.
Categories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependenceAVI-4557
go.drugbank.com/drugs/DB05447ExperimentalAVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently … Studies indicate that AVI-4557 can successfully reduce the rate of metabolism for certain drugs, therefore allowing greater and longer availability of the drug in the patient's system through a decrease