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Displaying results 6161 - 6170 of 10000 in total
  1. Drug

    ALT-P1

    go.drugbank.com/drugs/DB18485
    Investigational

    ALT-P1 is a long-acting recombinant human growth hormone fused to an alpha1-antitrypsin variant. It is under investigation for the treatment of growth hormone deficiency.

    Synonyms: Recombinant human growth hormone fused to alpha1-antitrypsin variant
  2. Drug

    Licogliflozin

    go.drugbank.com/drugs/DB15048
    Investigational

    Licogliflozin is under investigation in clinical trial NCT03320941 (A Dose-finding Study to Evaluate the Change in Weight After Treatment With LIK066 in Japanese Patients With Obesity).

    Categories: Sodium-Glucose Transporter 2 Inhibitors
  3. Drug

    Elastin (human)

    go.drugbank.com/drugs/DB15364
    Experimental

    Elastin (human) is under investigation in clinical trial NCT01466413 (Two Formulations of ELAPR Compared to Restylane® Vital Light Following Repeat Implants in the Upper Arm Dermis).

    Synonyms: SH-POLYPEPTIDE-50
  4. Drug

    SJG-136

    go.drugbank.com/drugs/DB11965
    Investigational

    SJG-136 has been used in trials studying the treatment of Recurrent Fallopian Tube Cancer, Secondary Acute Myeloid Leukemia, de Novo Myelodysplastic Syndromes, Recurrent Ovarian Epithelial Cancer, and

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-Ring
  5. Drug

    beta-Naphthoflavone

    go.drugbank.com/drugs/DB06732
    Experimental

    It may be a chemopreventive agent. … β-Naphthoflavone, also known as 5,6-benzoflavone, is a potent agonist of the aryl hydrocarbon receptor and induces cytochromes P450 (CYPs) and uridine 5'-diphospho-glucuronosyltransferases (UGTs).

    Categories: Cytochrome P-450 CYP1A2 Inducers, Heterocyclic Compounds, 1-RingSynonyms: 3-phenyl-1H-naphtho(2,1-b)pyran-1-one, β-NF
  6. Drug

    Vibriolysin

    go.drugbank.com/drugs/DB05135
    Experimental

    Vibriolysin is a proteolytic enzyme secreted by the marine microorganism Vibrio proteolyticus. … It is a new agent for enzymatic debridement, shown to rapidly and thoroughly hydrolyze burn wound eschar within full-thickness wounds.

  7. Drug

    TPMPA

    go.drugbank.com/drugs/DB16754
    Experimental

    [A245303] GABA<sub>C</sub> receptors are found primarily in the retina, although they may be present in other tissues, including the hippocampus, spinal cord, superior colliculus, pituitary and the gut … [A245308,A245313] TPMPA is used as a pharmacological probe for the investigation of GABA<sub>C</sub> receptor function.[A245313]

    Synonyms: P-Methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)phosphinic acid, Phosphinic acid, P-methyl-P-(1,2,3,6-tetrahydro-4-pyridinyl)-
  8. Drug

    APL-9

    go.drugbank.com/drugs/DB16460
    Investigational

    APL-9 is an investigational drug intended to centrally control the complement cascade at C3, potentially treating various diseases caused by excessive or uncontrolled complement activation. … It shares the same mechanism of action as Apellis’ lead compound, pegcetacoplan (APL-2), but with a lower molecular weight and shorter half-life.

  9. Drug

    SAR445136

    go.drugbank.com/drugs/DB17708
    Investigational

    [A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148] … SAR445136 is an investigational zinc finger nuclease gene-edited cell therapy.

  10. Drug

    MVC-COV1901

    go.drugbank.com/drugs/DB15854
    Investigational

    As of September 2020, the vaccine candidate is in Phase 1 clinical trials to assess its safety and immunogenicity (NCT04487210). … MVC-COV1901 is a vaccine candidate developed and commercialized by Medigen Vaccine Biologics Corporation. The vaccine candidate contains a perfusion form of the SARS-Cov2 recombinant spike protein.