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Pulocimab
go.drugbank.com/drugs/DB18938InvestigationalPulocimab is under investigation in clinical trial NCT06341335 (A Study of Ak104/placebo Plus Ak109/placebo and Paclitaxel in Gastric or Gastroesophageal Junction Adenocarcinoma).
Synonyms: Immunoglobulin g1, anti-(human vascular endothelial growth factor receptor 2) (human monoclonal ak109 .gamma.1-chain), disulfide with human monoclonal ak109 .kappa.-chain, dimerSertaconazole
go.drugbank.com/drugs/DB01153ApprovedSertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.
Categories: Heterocyclic Compounds, 1-RingProducts: ZALAIN 300 MG VAJINAL SUPOZITUVAR, 1 ADET, ZALAIN VAGINAL SUPPOSITORY 300 mgAntithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThymoglobulin is a mixture of antibodies intended to bind to various cell surface antigens. The most common mode of action of Thymoglobulin is via selective depletion of T-cells. … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.
Categories: Immunoglobulin G, Increased T Lymphocyte DestructionSynonyms: r-ATG, Lapine T-lymphocyte immune globulinPentoxyverine
go.drugbank.com/drugs/DB11186ApprovedWithdrawnPentoxyverine acts on sigma-1 receptors, as well as kappa and mu-opioid receptors. The FDA withdrew the use of all oral gel drug products containing pentoxyverine citrate. … Pentoxyverine, also referred to as carbetapentane, is a non-opioid central acting antitussive with antimuscarinic, anticonvulsant [A32717], and local anesthetic properties.
Mixtures: GAYABEN 150 ML SURUP, V-cofProducts: PENTOXYVERIN AL 1.35 MG/ML, Mucomat Hustenstiller 2,13 mg/ml Lösung zum EinnehmenPhosmet
go.drugbank.com/drugs/DB11448ExperimentalVet approvedPhosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingSynonyms: S-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl] O,O-dimethyl dithiophosphate, S-((1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl)phosphorodithioic acid O,O-dimethyl esterCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalOne of the most common uses for this drug is for a condition called _allergic rhinitis_. … The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms.
Mixtures: ACERADOX® G, GRIPAC 4®Categories: P-glycoprotein inhibitors, P-glycoprotein substratesErenumab
go.drugbank.com/drugs/DB14039ApprovedInvestigationalErenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … It is composed of 2 heavy chains, each containing 456 amino acids, and 2 light chains of the lambda subclass, each containing 216 amino acids, with an approximate molecular weight of 150 kDa [FDA Label
Products: PASURTA® 140 MG /ML, PASURTA® 70MG/MLBilastine
go.drugbank.com/drugs/DB11591ApprovedBilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.
Categories: Heterocyclic Compounds, 2-Ring, Heterocyclic Compounds, 1-RingProducts: ELHIST ® 20 MG, NAIRE® 20 MG TABLETABurosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalThis is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of rickets. … X-linked hypophosphatemia causes low circulating levels of phosphorus in the blood.
Categories: Fibroblast Growth Factor-23 Blocking AntibodiesProducts: CRYSVITA® SOLUCIÓN PARA INYECCIÓN 20 MG/ML, CRYSVITA® SOLUTION FOR INJECTION 30 MG/MLColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961.
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: Colctab 1 mg Tabletten, Colchanova 1 mg Tabletten