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Inactivated SARS-CoV-2 Vaccine (Chinese Academy of Medical Sciences)
go.drugbank.com/drugs/DB15863ExperimentalAs of June, 2020, safety and Immunogenicity trials are currently underway for this vaccine (NCT04470609 & NCT04412538). … The SARS-CoV-2 Inactivated Vaccine is a purified vaccine that contains multiple antigens from the virus and is inactivated in Vero Cells[A219758].
Enpatoran
go.drugbank.com/drugs/DB16501InvestigationalIt was investigated for systemic lupus erythematosus and cutaneous lupus erythematosus in completed trials (NCT04647708 and NCT05162586) and in a recruiting trial (NCT05540327). … Additionally, M5049 was studied for COVID-19 pneumonia in a completed trial with results (NCT04448756) and is currently being recruited for a trial involving participants with dermatomyositis and polymyositis
Tizaterkib
go.drugbank.com/drugs/DB21296InvestigationalTizaterkib has a monoisotopic molecular weight of 494.2 Da. … Tizaterkib is a small molecule drug. The usage of the INN stem '-terkib' in the name indicates that Tizaterkib is a extracellular signal-regulated kinase (ERK) inhibitor.
Ibrigampar
go.drugbank.com/drugs/DB05490InvestigationalT131 is a selective modulator of PPARg (peroxisome proliferator activated receptor gamma), a receptor involved in regulating the body’s ability to respond to insulin. … AMG-131 (T131), an orally-administered therapy, is expected to lower blood glucose in type II diabetic patients by improving the body’s ability to respond to insulin.
6-amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one
go.drugbank.com/drugs/DB08267ExperimentalThe introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. It is known to target queuine tRNA-ribosyltransferase. … 6-amino-4-(2-phenylethyl)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety.
Faxeladol
go.drugbank.com/drugs/DB20529InvestigationalFaxeladol is a small molecule drug. The usage of the INN stem '-adol/-adol-' in the name indicates that Faxeladol is a analgesic. … Effect of Food on it).
Menaquinone 6
go.drugbank.com/drugs/DB14936InvestigationalMenaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
Categories: Vitamins (Fat Soluble)Menaquinone
go.drugbank.com/drugs/DB15381InvestigationalMenaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists).
Categories: Vitamins (Fat Soluble)Natural Killer Cell
go.drugbank.com/drugs/DB15721InvestigationalThe most standard and utilized source of NK cells is directly from the peripheral blood of a donor through leukapheresis: a technique where immune cells are separated from red blood cells. … It is also possible to culture UCB CD34+ hematopoietic stem cells (HSCs) under stimulation of IL-2, IL-15, and stem cell factor (SCF) in a system to develop NK cells.
Nizubaglustat
go.drugbank.com/drugs/DB21603InvestigationalNizubaglustat is a small molecule drug. The usage of the INN stem '-glustat' in the name indicates that Nizubaglustat is a ceramide glucosyltransferase inhibitor. … Nizubaglustat has a monoisotopic molecular weight of 433.23 Da.
Synonyms: AZ-3102