Search
Dienogest
go.drugbank.com/drugs/DB09123ApprovedInvestigationalIt is a derivative of 19-nortestosterone and has antiandrogenic properties. … It is primarily used as a contraceptive in combination with ethinylestradiol, or in other combination form pills approved in United States and Europe however it is not available in the US by itself.
Synonyms: 17-alpha-Cyanomethyl-17-beta-hydroxy-estra-4,9(10)-dien-3-one, 17alpha-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrileMixtures: Foxinette 0,03 mg/2 mg 21+7 - Filmtabletten, Velbienne 1 mg/2 mg FilmtablettenUridine triacetate
go.drugbank.com/drugs/DB09144ApprovedIt reduces toxicity and cell-death associated with two cytotoxic intermediates: 5-fluoro-2'-deoxyuridine-5'-monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP). … As a result of UMPS deficiency, patients experience a systemic deficiency of pyrimidine nucleotides, accounting for most symptoms of the disease.
Synonyms: 2',3',5'-tri-O-acetyluridine, 2',3',5'-TriacetyluridineCategories: Heterocyclic Compounds, 1-RingIron sucrose
go.drugbank.com/drugs/DB09146ApprovedInvestigationalIron sucrose (sucroferric oxyhydroxide or iron saccharate) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis
International brands: Ferosoft SMixtures: Marnatal FTechnetium Tc-99m exametazime
go.drugbank.com/drugs/DB09163ApprovedExametazime, also known as hexamethylpropyleneamine oxime or HMPAO, acts as a chelating agent for the Tc-99m radioisotope. … Technetium Tc-99m exametazime is a radiopharmaceutical sold under the trade name Ceretec used in the detection of altered regional cerebral perfusion in stroke and other cerebrovascular diseases.
Categories: Compounds used in a research, industrial, or household settingBrifentanil
go.drugbank.com/drugs/DB09172ExperimentalIllicitBrifentanil (also known as A-3331) is an analog of fentanyl, a potent opioid. This drug is classified as an opioid analgesic and was developed in the early 1990s.
Categories: Heterocyclic Compounds, 1-RingAmedalin
go.drugbank.com/drugs/DB09188ExperimentalAmedalin is a selective norepinephrine reuptake inhibitor developed in the 1970s.
Synonyms: 3-methyl-3-(3-(methylamino)propyl)-1-phenyl-2-indolinoneCiglitazone
go.drugbank.com/drugs/DB09201ExperimentalCiglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones. … Ciglitazone is a potent and selective PPARγ ligand with an EC50 of 3.0 µM. It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsDroxicam
go.drugbank.com/drugs/DB09215ApprovedWithdrawnDroxicam is an oxicam non-steroidal anti-inflammatory drug and a prodrug of [DB00554].
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingTolfenamic acid
go.drugbank.com/drugs/DB09216ApprovedTolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. … It is used in the UK as a treatment for migraine under the name of Clotam.[L1292] In the US, it presents a Status class I by the FDA.
Categories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDSProducts: TOLFEDINE 4% W/V SOLUTION FOR INJECTION FOR DOGS AND CATS, Tolfine Solution for Injection 4.0% W/VNicorandil
go.drugbank.com/drugs/DB09220ApprovedInvestigationalWithdrawnIt is a niacinamide derivative that induces vasodilation of arterioles and large coronary arteries by activating potassium channels. … Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular
Synonyms: N-(2-Hydroxyethyl)nicotinamide nitrate, N-(2-Hydroxyethyl)nicotinamide nitrate (ester)International brands: K-Cor