Iron sucrose is an compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD). Due to less side effects than iron dextran, iron sucrose is more preferred in chronic kidney disease patients.
- Mechanism
- Curator reviewed
Following intravenous administration, iron sucrose is dissociated into iron and sucrose and the iron is transported as a complex with transferrin to target cells including erythroid precursor cells. The iron is then incorporated into hemoglobin as the cells mature into red blood cells.
- Primary indication
- Iron sucrose is elemental iron as an injection.Curator reviewed · 1 structured indication
- Formula / weight
- C12H29Fe5Na2O23 · 866.546 g/mol (avg)
- First approval
- Canada, 2018 · United States, 2000 · European Union, 2020
- Also known as
- Ferric hydroxide sucrose complex · Iron oxide saccharated · Iron saccharate · Iron sucrose complex · Iron sugar
- Code names
- XI 921
- Brand names
Resolves to
FWZTTZUKDVJDCM-CEJAUHOTSA-MSMILESO.O.O.[OH-].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[O--].[Na+].[Na+].[Fe+3].[Fe+3].[Fe+3].[Fe+3].[Fe+3].OC[C@H]1O[C@@](CO)(O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@@H]1OWhat you can answer from here — as of July 10, 2026
Which other approved drugs treat the same conditions as Iron sucrose, and which companies have late-stage candidates in those indications?
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