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Olcegepant
go.drugbank.com/drugs/DB04869InvestigationalBoehringer Ingelheim Pharmaceuticals’ olcegepant (BIBN 4096) is a selective Calcitonin Gene-Related Peptide (CGRP) antagonist, a new class of drugs in development for the treatment of acute migraine attacks … Olcegepant is undergoing phase II trials in Europe and the US, with preliminary results suggesting that CGRP antagonists may represent a potential new approach to the treatment of migraine.
Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalWhile many contain a conserved set of proteins, they also carry unique tissue type-specific proteins. … Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes.
Menatetrenone
go.drugbank.com/drugs/DB12148InvestigationalMenatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
Categories: Vitamins (Fat Soluble)SCB-2019
go.drugbank.com/drugs/DB15805InvestigationalAs of June 2020, the company is pursuing a randomized, double blind, placebo controlled study (NCT04405908) to test the safety and immunogenicity of the vaccine. … SCB-2019 is a recombinant trimeric S protein subunit vaccine candidate being investigated against COVID-19.
CoVac-1
go.drugbank.com/drugs/DB16429InvestigationalT-cell immunity[A226588]. … Sponsored by the University Hospital Tuebingen in Germany, CoVac-1 is a multi-peptide COVID-19 vaccine candidate created from HLA class I and HLA-DR T-cell epitopes of the S-protein[A226588].
Oxaprotiline
go.drugbank.com/drugs/DB09307ExperimentalOxaprotiline is a racemic mixture of the isomers levoprotiline and dextroprotiline. Levoprotiline is the R or levo isomer of oxaprotiline (CGP-12,103-A). … Dextroprotiline is the S or dextro isomer of oxaprotiline (CGP-12,104-A).
Dendritic cells vaccine
go.drugbank.com/drugs/DB15803InvestigationalAs of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia.
PH-284
go.drugbank.com/drugs/DB05452ExperimentalPH-284 belongs to a new family of new chemical entities called vomeropherins. … Vomeropherins are self-administered by the patient with a metered nasal spray, or nasal aerosol device so that they can bind to peripheral chemosensory receptors in the nasal passages.