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Linezolid
go.drugbank.com/drugs/DB00601ApprovedInvestigationalLinezolid is a synthetic antibiotic which is used for the treatment of infections caused by aerobic Gram-positive bacteria. … bacterial protein synthesis - more specifically, it binds to the 23S ribosomal RNA of the 50S subunit[A11227,A199050] and, in doing so, prevents the formation of the 70S initiation complex which is essential for
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Zyvoxid 100 mg/5 ml - Granulat zur Herstellung einer Suspension zum Einnehmen, ZYVOX SOLUTION FOR INFUSION 2 mg/mlRadium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalIt was first approved by the FDA in May 2013 and is currently marketed under the brand name Xofigo, which was formerly called Alpharadin. … The FDA label includes a warning that Radium Ra 223 Dichloride should not be used in women who are pregnant or may become pregnant due to the high risk of fetal harm.
Products: XOFIGO SOLUTION FOR INJECTION 1100kBq/ML, Xofigo (Radium-223 Dichloride) 1100 kBq/mL Solution for InjectionAsparaginase Escherichia coli
go.drugbank.com/drugs/DB00023ApprovedInvestigationalAsparaginase derived from _Escherichia coli_ (L-asparagine amidohydrolase, EC 3.5.1.1) is an enzyme responsible for the metabolism of L-asparagine, by catalyzing L-asparagine into L-aspartic acid and ammonia … It also facilitates the production of oxaloacetate which is needed for general cellular metabolism.
Products: LEUNASE FOR INJECTION 10,000 iu/vial, /Durchstechflasche Pulver zur Herstellung einer Injektions-/InfusionslösungSimvastatin
go.drugbank.com/drugs/DB00641ApprovedInvestigational[A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD. … as well as the need for surgical revascularization or angioplasty following a heart attack.
Categories: Hypolipidemic Agents Indicated for Hyperlipidemia, P-glycoprotein inhibitorsProducts: Mar-simvastatin, SIMVASTATIN Q-PH 10MG FTATechnetium Tc-99m sestamibi
go.drugbank.com/drugs/DB09161ApprovedInvestigationalCurrently available within a preparation kit for injection, Technetium Tc 99m Sestamibi is indicated for: 1) detecting coronary artery disease by localizing myocardial ischemia (reversible defects) and … infarction (non-reversible defects); and 2) evaluating myocardial function and developing information for use in patient management decisions.
Categories: P-glycoprotein substratesProducts: Kit for the Preparation of Technetium Tc99m SestamibiTestosterone undecanoate
go.drugbank.com/drugs/DB13946ApprovedInvestigational[A246594] There are oral and intramuscular formulations available for testosterone undecanoate: both formulations are indicated for testosterone replacement therapy in adult males with hypogonadism. … [L35970,L8932,L41355] Testosterone is a critical male hormone that is responsible for the normal growth and development of the male sex organs and for the maintenance of secondary sex characteristics
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: NEBIDO 1000MG SOLUTION FOR INJECTIONPseudotsuga menziesii pollen
go.drugbank.com/drugs/DB10986ApprovedPseudotsuga menziesii pollen is the pollen of the Pseudotsuga menziesii plant. Pseudotsuga menziesii pollen is mainly used in allergenic testing.
Synonyms: Douglas fir pollen extractProducts: Douglas Fir PollenPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalCurrently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Products: TAKIPRIL SOLUTION FOR INJECTION 20MG/ML, Takipril 20mg/ml Solution for InjectionHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnThere is no specific treatment for hepatitis. … The incubation period may be as long as 6 months, followed by a very complex clinical course of an acute or chronic nature, often leading to hospitalization.
Mixtures: Hexaxim Suspension for InjectionCategories: Antiinfectives for Systemic UseTramadol
go.drugbank.com/drugs/DB00193ApprovedInvestigational[A182300] Similar to other opioid medications, tramadol poses a risk for development of tolerance, dependence and abuse. … Due to its good tolerability profile and multimodal mechanism of action, tramadol is generally considered a lower-risk opioid option for the treatment of moderate to severe pain.
Mixtures: Mar-tramadol/acet, NODOL MAX® TABLETA RECUBIERTACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates