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Lenalidomide
go.drugbank.com/drugs/DB00480ApprovedInvestigational[A228553] It is a 4-amino-glutamyl analogue of [thalidomide] [A228543] and like thalidomide, lenalidomide exists as a racemic mixture of the active S(-) and R(+) forms. … [A228708] Available as oral capsules, lenalidomide is approved by the FDA and EU for the treatment of multiple myeloma, myelodysplastic syndromes, mantle cell lymphoma, follicular lymphoma, and marginal
Synonyms: 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline, 3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dioneCategories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesLamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalIt is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV). … A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.
Synonyms: (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine, beta-L-2',3'-Dideoxy-3'-thiacytidineMixtures: ABACAVIR E LAMIVUDINA DR. REDDY'S, ZOVILAM PED DT®5-Iodo-2'-Deoxyuridine-5'-Monophosphate
go.drugbank.com/drugs/DB02324ExperimentalSynonyms: 5-Iodo-2'-Deoxyuridine-5'-Monophosphate5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE
go.drugbank.com/drugs/DB06958ExperimentalSynonyms: 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDEClindamycin
go.drugbank.com/drugs/DB01190ApprovedInvestigationalVet approvedClindamycin is a semi-synthetic lincosamide antibiotic used in the treatment of a variety of serious infections due to susceptible microorganisms[L11599,L11596] as well as topically for acne vulgaris. … The name lincomycin is derived from Lincoln, Nebraska, where it was first isolated from _Streptomyces lincolnensis_ found in a soil sample.[A190621]
Synonyms: Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-alpha-D-galacto-octopyranoside, 7(S)-Chloro-7-deoxylincomycinInternational brands: Dalacin T Topical Solution, Dalacin CIomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigational[A265090,A265095] Iomeprol first appeared in the market in 1994 [A265095] and is currently used in various diagnostic processes involving x-ray imaging and computed tomography (CT) scans.[L52260] … Iomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use.
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Media, IodinatedSynonyms: N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-(N-METHYLGLYCOLAMIDO)ISOPHTHALAMIDE, 1,3-BENZENEDICARBOXAMIDE, N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-((HYDROXYACETYL)METHYLAMINO)-2,4,6-TRIIODO-Nickel sulfate
go.drugbank.com/drugs/DB14180ApprovedNickel sulfate is used in allergenic testing.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Nickel sulfate(1:1)Brivudine
go.drugbank.com/drugs/DB03312ApprovedInvestigationalBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Categories: Heterocyclic Compounds, 1-RingSynonyms: (E)-5-(2-Bromovinyl)-deoxyuridine1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREA
go.drugbank.com/drugs/DB07622ExperimentalSynonyms: 1-(3-(2,4-DIMETHYLTHIAZOL-5-YL)-4-OXO-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-5-YL)-3-(4-METHYLPIPERAZIN-1-YL)UREAEsuberaprost
go.drugbank.com/drugs/DB18464InvestigationalEsuberaprost (GP-1681), a drug intended for participants with pulmonary arterial hypertension, was under investigation in clinical trial NCT03657095 to evaluate its efficacy and safety.
Synonyms: (+)-4-((1r,2r,3as,8bs)-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-oct-1-en-6-yn-1-yl)-2,3,3a,8b-tetrahydro-1h-cyclopenta(b)(1)benzofuran-5-yl)butanoic acid, 1h-cyclopenta(b)benzofuran-5-butanoic acid, 2,3,3a,8b-tetrahydro-2-hydroxy-1-((1e,3s,4s)-3-hydroxy-4-methyl-1-octen-6-ynyl)-, (1r,2r,3as,8bs)-