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ATG003
go.drugbank.com/drugs/DB05069InvestigationalATG003, a novel anti-angiogenic drug candidate and a formulation of mecamylamine, is currently in clinical development for neovascular age-related macular degeneration.
Tifuvirtide
go.drugbank.com/drugs/DB05413InvestigationalTifuvirtide is the first members of a new class of anti-HIV drugs which is also called fusion inhibitors. It has received fast-track designation from the FDA and is in Phase I/II clinical testing.
Categories: Amino Acids, Peptides, and ProteinsLC16M8
go.drugbank.com/drugs/DB05019InvestigationalIt is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection. … LC16m8 is a next-generation, attenuated smallpox vaccine that is designed to have a better safety profile, yet be equally effective, compared to conventional smallpox vaccines.
13-deoxydoxorubicin
go.drugbank.com/drugs/DB05706InvestigationalGPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.
D-Asparagine
go.drugbank.com/drugs/DB03943ExperimentalA non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from ASPARTIC ACID and AMMONIA by asparagine synthetase. … (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Calcimycin
go.drugbank.com/drugs/DB19408InvestigationalCalcimycin is an ionophore and polyether antibiotic derived from Streptomyces chartreusensis. … It binds to and transports calcium and other divalent cations across membranes, disrupts oxidative phosphorylation, and inhibits ATPase in rat liver mitochondria.
Categories: Benzoxazoles and derivatives, Compounds used in a research, industrial, or household settingTetrahydrocannabivarin
go.drugbank.com/drugs/DB11755InvestigationalAlthough THCV possesses an almost identical structure to Δ9-THC (varying only by the length of its lipophilic alkyl chain), it has different molecular targets and pharmacological profile [A32972]. … Cannabinoid receptors are utilized endogenously by the body through the endocannabinoid system, which includes a group of lipid proteins, enzymes, and receptors that are involved in many physiological
Bergamot oil
go.drugbank.com/drugs/DB14335InvestigationalBergamot oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Categories: Compounds used in a research, industrial, or household settingSatraplatin
go.drugbank.com/drugs/DB04996InvestigationalAs an investigation drug, it has not yet received U.S. Food and Drug Administration (FDA) approval and is not available in retail pharmacies. … Satraplatin is a platinum compound that is currently under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy.
Categories: Antineoplastic and Immunomodulating AgentsXP21279
go.drugbank.com/drugs/DB06319InvestigationalXP21279 was under investigation in clinical trial NCT00914602 (An Exploratory Study of XP21279 (With Lodosyn®) and Sinemet® in Parkinson's Disease Subjects), administered in combination with [Carbidopa … XP21279 is a prodrug of [Levodopa], a dopamine precursor used in the management of Parkinson's disease.