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Acumapimod
go.drugbank.com/drugs/DB15448InvestigationalAcumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
Candoxatrilat
go.drugbank.com/drugs/DB11623ExperimentalA dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy
TAS-102
go.drugbank.com/drugs/DB08937InvestigationalTrifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis. Tipiracil prevents trifluridine from being broken down when taken orally.
PMI-001
go.drugbank.com/drugs/DB05730ExperimentalPMI-001 is a stand-alone, disease-modifying, anti-rheumatic drug (DMARD) being developed by Phytomedics Inc.
Enlonstobart
go.drugbank.com/drugs/DB21890Investigational[A274486] It targets the programmed cell death protein 1 (PD-1), is being developed by the CSPC Pharmaceutical Group for the treatment of advanced cervical cancer and other solid tumours.
ReN001
go.drugbank.com/drugs/DB05236InvestigationalReN001 a strong candidate for one of the first cell-based IND applications to be submitted to the Food and Drug Administration in the United States for consideration for the treatment of stroke in humans
V591
go.drugbank.com/drugs/DB16438InvestigationalThrough Merck’s acquisition of Thermis in May 2020, they were able to leverage Thermis’ platform knowledge and accelerate the development of V591 to phase I clinical trials (NCT04498247)[L30593].
Metrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedIt is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Etiracetam
go.drugbank.com/drugs/DB11868ExperimentalEtiracetam is under investigation in clinical trial NCT01137110 (Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)).
Moschus berezovskii musk sac resin
go.drugbank.com/drugs/DB14247InvestigationalIt is not an approved drug.