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Interleukin-10
go.drugbank.com/drugs/DB12880InvestigationalInterleukin-10 has been used in trials studying the prevention and treatment of Vasculitis, Pancreatitis, Bile Duct Diseases, Pancreatic Diseases, and Gallbladder Diseases, among others.
Categories: Amino Acids, Peptides, and Proteins, Intercellular Signaling Peptides and ProteinsTalmapimod
go.drugbank.com/drugs/DB05412InvestigationalTalmapimod is the first-generation oral p38 MAP kinase inhibitor developed by Scios. It has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.
Tezacitabine
go.drugbank.com/drugs/DB06433InvestigationalA synthetic purine nucleoside analogue with potential antineoplastic activity.
Categories: Nucleic Acids, Nucleotides, and NucleosidesMVA-BN-brachyury-TRICOM vaccine
go.drugbank.com/drugs/DB17424InvestigationalIt is composed of recombinant vaccinia viral vector, modified vaccinia Ankara-Bavarian Nordic (MVA-BN), encoding the human transcription factor and tumour-associated antigen (TAA) brachyury, and a triad … MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine.
Droloxifene
go.drugbank.com/drugs/DB15641ExperimentalDroloxifene may have an effect on bone and breast tissue because it induces apoptosis. … Short-term toxicity was generally mild, and similar to that seen with other antiestrogens. Droloxifene appears active and tolerable.
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsAVN-944
go.drugbank.com/drugs/DB05500Investigational, DNA replication, apoptosis and cell cycle control. … AVN944 is a biotech drug that demonstrated a statistically meaningful impact on IMPDH and other proteins that are critical to activities in cancer cells, including nucleotide biosynthesis, energy and metabolism
Cagrilintide
go.drugbank.com/drugs/DB18887InvestigationalWith Metformin With or Without an SGLT2 Inhibitor). … Cagrilintide is under investigation in clinical trial NCT06221969 (A Research Study to See How Much Cagrisema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated
Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone AntagonistsINCB13739
go.drugbank.com/drugs/DB05064InvestigationalIt is an orally available small molecule inhibitor of 11beta-HSD1 (11-beta hydroxysteroid dehydrogenase type 1). 11beta-HSD1 is an enzyme that appears to be critical to the development of type 2 diabetes
Dipropyl-4-hydroxytryptamine
go.drugbank.com/drugs/DB13990ExperimentalDipropyl-4-hydroxytryptamine was first synthesized by Alexander Shulgin. This agent and its properties haven't been fully elucidated.
CCR5 mAb
go.drugbank.com/drugs/DB05906ExperimentalCCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus ( … It was generated by HGS using the Abgenix XenoMouse technology.