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TC-2216
go.drugbank.com/drugs/DB06044InvestigationalTC-2216 is an investigational novel small molecule that is being developed as an oral treatment for depression and anxiety disorders. … TC-2216 showed greater potency than and anti-depressant effects comparable to selective serotonin reuptake inhibitors and tricyclics, which are commonly used treatments for depression, as well as anxiety-relieving
VLTS-589
go.drugbank.com/drugs/DB05430InvestigationalVLTS-589 consists of plasmid encoding the angiomatrix protein Del-1 in conjunction with poloxamer 188 for the treatment of peripheral vascular disease.
P-113D
go.drugbank.com/drugs/DB04987ExperimentalIt is being pursued as a potential treatment for cystic fibrosis by Demegen, Inc. … P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds found naturally in human saliva.
Synonyms: D-PEPTIDE OF THE SEQUENCE AKRHHGYKRKFH - NH2Amrinone
go.drugbank.com/drugs/DB01427ApprovedWithdrawnAmrinone (or inamrinone) is a type 3 pyridine phosphodiesterase inhibitor. It is used in the treatment of congestive heart failure.
Categories: Compounds used in a research, industrial, or household settingSovateltide
go.drugbank.com/drugs/DB06138InvestigationalIt is being developed as an adjunct to chemotherapy. … SPI-1620 is an endothelin B receptor agonist. In animal models SPI-1620 selectively and transiently increases tumor blood flow allowing increased delivery of anticancer agents to the tumor.
KOS-2187
go.drugbank.com/drugs/DB05946ExperimentalKOS-2187, a novel erythromycin-based motilin agonist, or motilide, as a clinical candidate for the treatment of gastrointestinal motility disorders such as gastroparesis and gastroesophageal reflux disease
Hexestrol
go.drugbank.com/drugs/DB07931ApprovedWithdrawnA synthetic estrogen that has been used as a hormonal antineoplastic agent.
Synonyms: Meso-3,4-di(p-hydroxyphenyl)-n-hexaneFleroxacin
go.drugbank.com/drugs/DB04576ExperimentalFleroxacin is a broad-spectrum antimicrobial fluoroquinolone. It strongly inhibits the DNA-supercoiling activity of DNA gyrase. Fleroxacin is not an inhibitor of CYP1A2.[A39048]
TGAAC09
go.drugbank.com/drugs/DB06363InvestigationaltgAAC09 is an investigational vaccine that utilizes an AAV vector to deliver genes that encode HIV proteins.
Paliroden
go.drugbank.com/drugs/DB05454InvestigationalPaliroden is an orally active neurotrophic, non-peptidic compound that activates synthesis of endogenous neurotrophines.