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Opicapone
go.drugbank.com/drugs/DB11632ApprovedInvestigationalof these symptoms through the use of a dopamine agonist, a monoamine oxidase B inhibitor (selegiline, rasagiline), a _catechol-O-methyl transferase (COMT)_ inhibitor, or amantadine, or using a modified-release … [A36938, A203048] Many patients with Parkinson’s disease treated with levodopa plus a dopa decarboxylase (DDC) inhibitor (eg carbidopa) experience motor complications over time, which calls for the management
Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InhibitorsDibotermin alfa
go.drugbank.com/drugs/DB11639ApprovedInvestigationalDibotermin alfa is a recombinant human bone morphogenetic protein-2 (rhBMP-2) derived from a recombinant Chinese Hamster Ovary (CHO) cell line [FDA Label]. … BMP-2 is a potent osteoinductive protein that plays a critical role in the differentiation of osteoprogenitor cells into osteoblasts, thus promoting bone and cartilage formation [A31952].
Synonyms: BMP 2, BMP-2HT-0712
go.drugbank.com/drugs/DB11650InvestigationalBLX-028914 has been used in trials studying the treatment and basic science of Allergic Rhinitis and Age-Associated Memory Impairment (AAMI).
Categories: Heterocyclic Compounds, 1-RingDactolisib
go.drugbank.com/drugs/DB11651InvestigationalDactolisib has been used in trials studying the treatment of Cancer, Solid Tumor, Renal Cancer, Breast Cancer, and Cowden Syndrome, among others.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRebamipide
go.drugbank.com/drugs/DB11656ApprovedInvestigationalRebamipide has been investigated for the treatment of Stomach Ulcer, Keratoconjunctivitis Sicca, and Gastric Adenoma and Early Gastric Cancer.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingQAV-680
go.drugbank.com/drugs/DB11658InvestigationalQAV680 has been used in trials studying the treatment of Asthma, Allergic Rhinitis, and Seasonal Allergic Rhinitis.
Categories: Heterocyclic Compounds, 2-RingPsilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Categories: Heterocyclic Compounds, 2-RingSP-8203
go.drugbank.com/drugs/DB11670InvestigationalSP-8203 has been used in trials studying the treatment of Ischemic Stroke.
Categories: Heterocyclic Compounds, 2-RingAZD-4877
go.drugbank.com/drugs/DB11671InvestigationalAZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
Categories: Heterocyclic Compounds, 1-RingEquol
go.drugbank.com/drugs/DB11674InvestigationalEquol has been used in trials studying the treatment of Breast Cancer.
Synonyms: S-equolCategories: Heterocyclic Compounds, 2-Ring