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Staurosporine
go.drugbank.com/drugs/DB02010ExperimentalAn indolocarbazole that is a potent protein kinase C inhibitor which enhances cAMP-mediated responses in human neuroblastoma cells. (Biochem Biophys Res Commun 1995;214(3):1114-20)
Maytansine
go.drugbank.com/drugs/DB19582InvestigationalMaytansine is under investigation in clinical trial NCT04189211 (A Clinical Trial of BAT8001 on Safety, Tolerability and Pharmacokinetics for Patients).
Chlorcyclizine
go.drugbank.com/drugs/DB08936ApprovedChlorcyclizine also has some local anesthetic, anticholinergic, and antiserotonergic properties, and can be used as an antiemetic.
RD06-04
go.drugbank.com/drugs/DB24647InvestigationalRD06-04 is under investigation in clinical trial NCT06986018 (Clinical Study on the Targeted CD19 Universal CAR-T Cell Injection (RD06-04) for the Treatment of IIM and AAV).
CPG 10101
go.drugbank.com/drugs/DB05530InvestigationalCPG 10101 is a synthetic oligodeoxynucleotide (ODN) in clinical trials.
PDPSC18
go.drugbank.com/drugs/DB05167ExperimentalPDPSC18 is therapeutic DNA vaccine designed to fight chronic infections with the Hepatitis B virus, entering phase I clinical trials.
Topsalysin
go.drugbank.com/drugs/DB05160InvestigationalTopsalysin is being developed for the treatment of localized prostate cancer and also benign prostatic hyperplasia. Topsalysin is delivered locally to the prostate under ultrasound guidance.
MG98
go.drugbank.com/drugs/DB06544ExperimentalMG98, a second-generation antisense oligodeoxynucleotide inhibitor of human DNMT1, was investigated in the completed clinical trial NCT00003890 for treating patients with advanced solid tumors.
PR-15
go.drugbank.com/drugs/DB06037InvestigationalPR-15 is a novel anti-platelet protein with the potential to treat arterial thrombosis occurring during acute coronary syndromes without the bleeding risk associated with existing agents.