Search

Displaying results 621 - 630 of 10000 in total
  1. Drug

    Digoxin

    go.drugbank.com/drugs/DB00390
    ApprovedInvestigational

    [L9143] This drug originates from the foxglove plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and botanist in the 1780s. … [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954.

    Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein substrates with a Narrow Therapeutic IndexInternational brands: Digocard-G
  2. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    Ramiprilat is a potent, competitive inhibitor of ACE, the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII). … Ramipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys.

    Synonyms: (2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acidMixtures: RAMIPRIL COMP HEU 5/25MG N, DELMUNO 5/5 MG
  3. Indication

    Tyrosinemia Type 1

    go.drugbank.com/conditions/DBCOND0091509
    Drugs: Nitisinone
    Synonyms: Tyrosinemia I, Tyrosinemia type I
  4. Indication

    Primary Hyperoxaluria Type 1 (PH1)

    go.drugbank.com/conditions/DBCOND0080300
    Drugs: Lumasiran · Nedosiran
    Synonyms: PH I, Oxalosis type I
  5. Indication

    Hypofibrinogenemia, Congenital

    go.drugbank.com/conditions/DBCOND0069187
    Drugs: Fibrinogen human
    Synonyms: Deficiency factor I, Factor I deficiency
  6. Indication

    No suitable human leukocyte antigen (HLA)-matched related stem cell donor

    go.drugbank.com/conditions/DBCOND0173823
    Drugs: Etuvetidigene Autotemcel
    Synonyms: No suitable human leukocyte antigen (HLA)-matched related stem cell donor
  7. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated … Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: YARDIX® 240MG, TECFIDERA® 240MG
  8. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527] … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.

    Synonyms: 1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-olMixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5
  9. Drug

    Oxycodone

    go.drugbank.com/drugs/DB00497
    ApprovedIllicitInvestigational

    [A178696] It is currently indicated as an immediate release product for moderate to severe pain and as an extended release product for chronic moderate to severe pain requiring continuous opioid analgesics … [Label] The first oxycodone containing product, Percodan, was approved by the FDA on April 12, 1950.[L6460]

    Synonyms: 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, 4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-oneMixtures: OXYCODON/NALOXON-NX 10/5, OXYCODON/NALOXON-NX 10/5
  10. Drug

    Protamine

    go.drugbank.com/drugs/DB13700
    ApprovedInvestigationalWithdrawn

    Products: PROTAMYN 1000® UI/ML AMPOLLA, PROTAMİN ICN 5000 IU/5ML IV KULLANIM İÇİN ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 ADET