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Displaying results 621 - 630 of 10000 in total
  1. Drug

    Icatibant

    go.drugbank.com/drugs/DB06196
    ApprovedInvestigational

    It is resistant to bradykinin-cleaving enzyme degradation and has a potency of 2-3 times higher than earlier B<sub>2</sub> receptors antagonists, thus representing a new class of medication. … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.

    Products: ICATIBANT DR. REDDY'S
  2. Drug

    Acyclovir

    go.drugbank.com/drugs/DB00787
    ApprovedInvestigational

    [L7303,L7315,L7318,L7321,L7324,L7327] Acyclovir is generally used first line in the treatment of these viruses and some products are indicated for patients as young as 6 years old. … [L7321] Acyclovir was granted FDA approval on 29 March 1982.[L7318]

    Mixtures: Activir Duo 50 mg/g + 10 mg/g CremeProducts: AVIREX-U, ACICLOVIR AL 200
  3. Drug

    Coagulation Factor IX (Recombinant)

    go.drugbank.com/drugs/DB00100
    Approved

    It has a primary amino acid sequence that is identical to the Ala148 allelic form of human factor IX, and has structural and functional characteristics similar to those of endogenous factor IX. … medium that is then processed and purified for use as a pharmaceutical agent.

    Products: BENEFIX 1000 IU IV ENJEKSIYONLUK COZELTI ICIN TOZ VE COZUCU, BeneFIX powder and solvent for solution for injection 500 IU/VIAL.
  4. Drug

    Chlorpheniramine

    go.drugbank.com/drugs/DB01114
    ApprovedInvestigational

    One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.

    Mixtures: STEP-OUT, Ed A-hist DMCategories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    Regardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in … Interestingly enough, it is precisely via this mechanism why sildenafil was at first researched as a potential treatment for angina - or chest pain associated with inadequate blood flow to the heart -

    Synonyms: 1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazineCategories: combinations of sulfonamides
  6. Drug

    Edoxaban

    go.drugbank.com/drugs/DB09075
    ApprovedInvestigational

    Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. … (PE) following 5-10 days of initial therapy with a parenteral anticoagulant.

    Products: Ag-edoxaban
  7. Drug

    Montelukast

    go.drugbank.com/drugs/DB00471
    ApprovedInvestigational

    worldwide via millions of prescriptions annually and has since become available as a generic and as a brand name product. … [L6301] The medication is a member of the leukotriene receptor antagonist (LTRA) category of drugs.

    Mixtures: EVEREST-DX, DESLODEX® DUO TABLETAS RECUBIERTASProducts: MONTELUKAST DR. REDDY'S, Ag-montelukast
  8. Drug

    Etoposide

    go.drugbank.com/drugs/DB00773
    ApprovedInvestigational

    A semisynthetic derivative of podophyllotoxin that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. … Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

    Synonyms: 4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylidene-beta-D-glucopyranoside), 9-((4,6-O-Ethylidine-beta-D-glucopyranosyl)oxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,4-dimethyloxyphenyl)furo(3',4'':6,7)naptho-(2,3-d)-1,3-dioxol-6(5aH)-oneCategories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic Index
  9. Drug

    Tiapride

    go.drugbank.com/drugs/DB13025
    Investigational

    Tiapride is a selective D2 and D3 dopamine receptor blocker in the brain.

    Categories: Dopamine D2 Receptor AntagonistsProducts: TIAPRID AL 100MG TABLETTEN, TIAPRID AL 200MG TABLETTEN
  10. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … See toxicity section below for a complete listing of side effects.

    Categories: Combined Inhibitors of Serotonin/Norepinephrine Reuptake, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: ANAFRANIL® RETARD 75 MG TABLETAS RECUBIERTAS DE LIBERACION PROLONGADA