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Vinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalLike other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396]. … Having an incidence of 429,700 new cases per year worldwide, urothelial carcinoma of the bladder is one of the most common malignancies that mostly affects individuals aged 50–79 years [A32626].
Categories: Antineoplastic and Immunomodulating Agents, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine, 20',20'-difluoro-3',4'-dihydrovinorelbineFelodipine
go.drugbank.com/drugs/DB01023Approvedcyclic nucleotide phosphodiesterase, and blocks calcium influx through voltage-gated T-type calcium channels. … Felodipine is a long-acting 1,4-dihydropyridine calcium channel blocker (CCB)b.
Mixtures: DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET, DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, ramipril and felodipine2-Hydroxyestradiol
go.drugbank.com/drugs/DB07706Experimental2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol. [A31630]
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsSynonyms: (17β)-estra-1,3,5(10)-triene-2,3,17-triol, 2-OH-EstradiolSuzetrigine
go.drugbank.com/drugs/DB18927ApprovedInvestigational[A264953] On January 30, 2025, suzetrigine was approved by the FDA as a first-in-class non-opioid analgesic.[L52098] … Suzetrigine is a Na<sub>V</sub>1.8 voltage-gated sodium channel blocker with analgesic properties[A264948] Na<sub>V</sub>1.8 is abundantly expressed in peripheral sensory nerves to play a role in pain
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein substratesSynonyms: 4-[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5-dimethyl-5-(trifluoromethyl)oxolane-2-amido]pyridine2-carboxamide, 4-[(2R,3S,4S,5R)-3-(3,4-difluoro-2-methoxyphenyl)-4,5- dimethyl-5-(trifluoromethyl)oxolane-2- carboxamido]pyridine-2-carboxamidePyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approved, pyridoxal 5'-phosphate and pyridoxamine 5'-phosphate. … It's important to note that Vitamin B6 is the collective term for a group of three related compounds, pyridoxine, pyridoxal, and pyridoxamine, and their phosphorylated derivatives, pyridoxine 5'-phosphate
Mixtures: LYSOBACT 20 MG/10 MG PASTİL, 30 ADET, PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, Vitamin B Complex5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole
go.drugbank.com/drugs/DB08720Experimental5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole is a solid. This compound belongs to the phenol ethers. … These are aromatic compounds containing an ether group substituted with a benzene ring. This drug is known to target genome polyprotein.
Synonyms: 5-(5-(4-(4,5-dihydro-2-oxazoly)phenoxy)pentyl)-3-methyl osoxazole(3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE
go.drugbank.com/drugs/DB07222ExperimentalSynonyms: (3S)-N-(5-CHLORO-2-METHYLPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE{[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid
go.drugbank.com/drugs/DB08098ExperimentalThese are compounds containing a furan ring which bears a nitro group. It targets the protein aldose reductase.
Synonyms: {[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-yl]thio}acetic acid3-chloro-5-[2-chloro-5-(1H-indazol-3-ylmethoxy)phenoxy]benzonitrile
go.drugbank.com/drugs/DB08154ExperimentalSynonyms: 3-chloro-5-[2-chloro-5-(1H-indazol-3-ylmethoxy)phenoxy]benzonitrile5'-ACETYL-4-{[(2,4-DIMETHYLPHENYL)SULFONYL]AMINO}-2,2'-BITHIOPHENE-5-CARBOXYLIC ACID
go.drugbank.com/drugs/DB08556ExperimentalSynonyms: 5'-ACETYL-4-{[(2,4-DIMETHYLPHENYL)SULFONYL]AMINO}-2,2'-BITHIOPHENE-5-CARBOXYLIC ACID