Search
Dimenoxadol
go.drugbank.com/drugs/DB01461ExperimentalIllicitIn the United States it is classified as a Schedule I controlled drug. … Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative.
Trefentanil
go.drugbank.com/drugs/DB09181ExperimentalTrefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research. … Trefentanil (A-3665) is a fentanyl analogue opioid developed in 1992. It is more potent and shorter acting than alfentanil.
Categories: Heterocyclic Compounds, 1-RingAftobetin
go.drugbank.com/drugs/DB20425InvestigationalAftobetin is under investigation in clinical trial NCT02928211 (Aftobetin-HCl and Fluorescence Detection Measured by Sapphire II to Determine the Number and Timing of Administrations). … Aftobetin is a small molecule drug.
TAFA-93
go.drugbank.com/drugs/DB05887Experimental, the treatment of autoimmune and oncological diseases, and as a component of coated stents for the treatment of coronary artery disease. … TAFA93 is a novel prodrug of the mTOR inhibitor rapamycin which has successfully completed Phase 1 clinical development. mTOR inhibitors are currently used in the prevention of organ rejection in transplantation
WIN 55212-2
go.drugbank.com/drugs/DB13950ExperimentalIt is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling. … WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical
Salts: WIN 55212-2 mesylateCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingAnti-SARS-CoV-2 immunoglobulin
go.drugbank.com/drugs/DB16360InvestigationalHyperimmune immunoglobulin to SARS-CoV-2 (hIVIG) is obtained from the plasma of patients who recover from COVID-19 and develop neutralizing antibodies. … plasma](https://go.drugbank.com/drugs/DB15692) as the antibodies are highly purified and concentrated.
Categories: Immunoglobulin GSynonyms: Hyperimmune immunoglobulin to SARS-CoV-2, SARS-CoV-2 immunoglobulinAlphameprodine
go.drugbank.com/drugs/DB01499ExperimentalIllicitThe stereoisomer betameprodine is similarly classified, however alphameprodine is more widely used (both are referred to as Meprodine). Alphameprodine is a structural analogue of meperidine. … Alphameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances.
Synonyms: alpha-3-ethyl-1-methyl-4-phenyl-4-propionoxypiperidine, alpha-3-Ethyl-1-methyl-4-phenyl-4-propionyloxypiperidineBetameprodine
go.drugbank.com/drugs/DB01552ExperimentalIllicitThe stereoisomer alphameprodine is similarly classified, and was more widely used (both are referred to as Meprodine). Betameprodine is a structural analogue of meperidine. … Betameprodine is an opioid analgesic classified by the United States Drug Enforcement Administration under Schedule I of illegal substances.
Synonyms: beta-1-Methyl-3-ethyl-4-phenyl-4-propionoxy-piperidin, beta-3-Ethyl-1-methyl-4-phenyl-4-propionoxypiperidineEMZ702
go.drugbank.com/drugs/DB05021InvestigationalEMZ702 has an excellent safety profile and the combination of EMZ702 with interferon and ribavirin in surrogate models for hepatitis C has demonstrated a two to three fold increase in anti-viral potency … compared to interferon and ribavirin alone.
Triazavirin
go.drugbank.com/drugs/DB15622Investigational[L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625] … Triazavirin is a guanine nucleotide analog antiviral originally developed in Russia that has shown efficacy against influenza A and B, including the H5N1 strain.
Categories: Heterocyclic Compounds, 1-Ring