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Zastumotide
go.drugbank.com/drugs/DB14926InvestigationalIt is under investigation in clinical trial NCT00257738 (0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck). … Zastumotide is a recombinant MAGE-A3 Antigen-Specific Cancer Immunotherapeutic (MAGE-A3 ASCI) also known as astuprotimut-R.
DYNE-251
go.drugbank.com/drugs/DB18130InvestigationalIt is being investigated for the treatment of Duchenne muscular dystrophy (DMD) in patients who are amenable to exon 51 skipping. … DYNE-251 is a phosphorodiamidate morpholino oligomer (PMO) conjugated to a fragment antibody (Fab) that binds to the transferrin receptor 1 (TfR1).
RGX-501
go.drugbank.com/drugs/DB17639InvestigationalRGX-501 is an adeno-associated virus vector 8 (AAV8)-mediated gene therapy that delivers a functional copy of the human low-density lipoprotein receptor (LDLR) gene to liver cells. … It is being investigated for the treatment of homozygous familial hypercholesterolemia.[L46696]
Barbital
go.drugbank.com/drugs/DB01483ExperimentalIllicitBarbital is also used in veterinary practice for central nervous system depression. Barbital is a schedule IV controlled drug. … A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence.
Emricasan
go.drugbank.com/drugs/DB05408InvestigationalIt is developed by Pfizer and made in such a way that it protects liver cells from excessive apoptosis. … Emricasan is the first caspase inhibitor tested in human which has received orphan drug status by FDA.
Maxacalcitol
go.drugbank.com/drugs/DB06272InvestigationalCategories: Compounds used in a research, industrial, or household settingN-(3-Propylcarbamoyloxirane-2-Carbonyl)-Isoleucyl-Proline
go.drugbank.com/drugs/DB02855ExperimentalCategories: Compounds used in a research, industrial, or household settingSynonyms: N-(3-Propylcarbamoyloxirane-2-carbonyl)-isoleucyl-prolinevCP2292
go.drugbank.com/drugs/DB19292InvestigationalvCP2292 is under investigation in clinical trial NCT01982487 (Vaccine Therapy and IDO1 Inhibitor INCB024360 in Treating Patients With Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Who … Are in Remission).
Dorzagliatin
go.drugbank.com/drugs/DB15123InvestigationalDorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
Categories: Drugs Used in DiabetesEtigilimab
go.drugbank.com/drugs/DB18854InvestigationalEtigilimab is under investigation in clinical trial NCT04761198 (A Study of Etigilimab and Nivolumab in Subjects With Locally Advanced or Metastatic Tumors.).