Search

Displaying results 6341 - 6350 of 10000 in total
  1. Drug

    OSI-930

    go.drugbank.com/drugs/DB05913
    Investigational

    OSI-930 is an orally active inhibitor of two clinically validated targets: c-Kit and the vascular endothelial growth factor receptor-2 (VEGFR-2). … OSI-930 is designed to target both cancer cell proliferation and blood vessel growth (angiogenesis) in selected tumors.

  2. Drug

    Ceperognastat

    go.drugbank.com/drugs/DB21591
    Investigational

    Ceperognastat is under investigation in clinical trial NCT05063539 (A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease).

  3. Drug

    Telcagepant

    go.drugbank.com/drugs/DB12228
    Investigational

    It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. … Telcagepant has been investigated for the treatment of Migraine.

  4. Drug

    Col-118

    go.drugbank.com/drugs/DB05778
    Investigational

    COL-118, a topical compound based on the SansRosa technology, for the treatment of redness associated with rosacea and other skin disorders. … It is a believed to reduce erythema by constricting enlarged blood vessels in facial tissue.

  5. Drug

    Cephalothin Group

    go.drugbank.com/drugs/DB03450
    Experimental

    This compound belongs to the 1,3-thiazines. … This substance is known to target beta-lactamase Toho-1 and D-alanyl-D-alanine carboxypeptidase.

  6. Drug

    5-(5-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-(hydroxyethyl oxymethyleneoxymethyl) isoxazole

    go.drugbank.com/drugs/DB08721
    Experimental

    This compound belongs to the phenol ethers. … are aromatic compounds containing an ether group substituted with a benzene ring. 5-(5-(2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy)pentyl)-3-(hydroxyethyl oxymethyleneoxymethyl) isoxazole targets the

  7. Drug

    Deoxyribonuclease I

    go.drugbank.com/drugs/DB16523
    Investigational

    Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory … symptoms requiring parenteral antibiotics, aerosolized human DNase I has been administered to patients with cystic fibrosis[A227723].

  8. Drug

    Inositol 1,3-bisphosphate

    go.drugbank.com/drugs/DB02942
    Experimental

    The compound corresponds to the soluble headgroup of phosphatidylinositol 3-phosphate (PtdIns(3)P), an endosomal signaling lipid recognized by FYVE domains, and it has been used as a ligand in structural … Inositol 1,3-bisphosphate is a phosphorylated myo-inositol derivative and small molecule metabolite in which phosphate groups occupy the 1 and 3 positions of the inositol ring.

  9. Drug

    Citicoline

    go.drugbank.com/drugs/DB12153
    ApprovedInvestigationalWithdrawn

    It has been investigated for the treatment, supportive care, and diagnosis of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar Disorder, among others.

    Synonyms: citidin difosfato de colina
  10. Drug

    COCAINE ESTERASE (RBP-8000)

    go.drugbank.com/drugs/DB19225
    Investigational

    RBP-8000 is under investigation in clinical trials (A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse) for the treatment of Cocaine