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Displaying results 6341 - 6350 of 10000 in total
  1. Drug

    Methotrimeprazine

    go.drugbank.com/drugs/DB01403
    Approved

    It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine.

    Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin Receptor Antagonists
  2. Drug

    Cyclopropane

    go.drugbank.com/drugs/DB13984
    Experimental

    Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive. … Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene.

  3. Drug

    Cetrelimab

    go.drugbank.com/drugs/DB15421
    Investigational

    Cetrelimab is under investigation in clinical trial NCT03547037 (A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of JNJ-63723283, an Anti-Programmed Cell Death (PD … )-1 Monoclonal Antibody, as Monotherapy or in Combination With Erdafitinib in Japanese Participants With Advanced Solid Cancers).

  4. Drug

    ORG-34517

    go.drugbank.com/drugs/DB05423
    Investigational

    It has potential to treat a number of diseases such as Cushing’s disease, hypertension, diabetes, glaucoma etc, in which the activity of metabolites corticosterone and cortisol is high. … ORG-34517 is currently under investigation by Organon for the treatment of depression.

  5. Drug

    9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide

    go.drugbank.com/drugs/DB02842
    Experimental

    9-amino-n-[3-(dimethylamino)propyl]acridine-4-carboxamide is an inactive derivative of the antitumour agents N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (DACA) and 9-amino-DACA.

  6. Drug

    2'-Deoxyuridine

    go.drugbank.com/drugs/DB02256
    Investigational

    An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. … Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies. [PubChem]

  7. Drug

    QazCovid-in

    go.drugbank.com/drugs/DB16441
    Investigational

    The QazCovid-in vaccine, an inactivated vaccine, was developed and tested in the Kazakh Research Institute for Biological Safety Problems[L30628]. … It demonstrated high efficacy, safety, and immunogenicity at 96% in initial Phase I and II trials (NCT04530357), and will now be undergoing upcoming Phase III trials[L30633, L30638].

  8. Drug

    Gentian violet cation

    go.drugbank.com/drugs/DB00406
    Approved

    A dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.

  9. Drug

    9MW3011

    go.drugbank.com/drugs/DB24999
    Investigational

    The drug is an anti-TMPRSS6 (Transmembrane Serine Protease 6, also known as Matriptase-2) monoclonal antibody.[L54591, L54596] … 9MW3011 is a biologic drug. 9MW3011 is under investigation in clinical trial NCT06752746 (A Study of Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of 9MW3011 in Patients

  10. Drug

    Phensuximide

    go.drugbank.com/drugs/DB00832
    Approved

    The frequency of attacks is reduced by depression of nerve transmission in the motor cortex. … It suppresses the paroxysmal three cycle per second spike and wave EEG pattern associated with lapses of consciousness in petit mal seizures.