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Tolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedIt is sold under several brand names, most notably Tinactin and Odor Eaters. … Tolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.
Synonyms: 2-Naphthyl N-methyl-N-(3-tolyl)thionocarbamate, N-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamideMixtures: Terbinafine HCl Chlortimazole and TolnaftateFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity.
Categories: Calcium-Regulating Hormones and AgentsSynonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazineEscitalopram
go.drugbank.com/drugs/DB01175ApprovedInvestigational[A185420] It is used to restore serotonergic function in the treatment of depression and anxiety. … that the R-enantiomer of racemic citalopram actively dampens the activity of escitalopram rather than existing simply as an inactive enantiomer.
Products: CIPRALEX 10MG, Cipralex -10mgNortriptyline
go.drugbank.com/drugs/DB00540ApprovedInvestigational[L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881] … Nortriptyline hydrochloride, the active metabolite of [amitriptyline], is a tricyclic antidepressant (TCA).
Categories: Tricyclics and Other Norepinephrine-reuptake InhibitorsSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamineNilutamide
go.drugbank.com/drugs/DB00665ApprovedInvestigationalNilutamide is an antineoplastic hormonal agent primarily used in the treatment of prostate cancer. … Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors (but not for progestogen, estrogen, or glucocorticoid receptors).
Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related AgentsProducts: Anandron Tab 50mg, Anandron Tab 100mgRuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigational[A229708] In 2014, it was approved for the treatment of polycythemia vera in adults who have an inadequate response to or are intolerant of [hydroxyurea] and in 2019, ruxolitinib was approved for use in … Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Jakavi 10mg Tablets, JAKAVI TABLET 10MGTuroctocog alfa pegol
go.drugbank.com/drugs/DB14738ApprovedInvestigationalIt was developed by Novo Nordisk and approved by the US FDA on October 16, 2013 [L1104]. … Turoctocog alfa pegol is a pegylated version of [turoctocog alfa]. Novo Nordisk's brand name Esperoct (turoctocog alfa pegol, N8-GP) was approved by the US FDA on February 19, 2019.
Categories: Amino Acids, Peptides, and ProteinsProducts: ESPEROCT® 1500 UI, ESPEROCT® 2000 UIFluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approved[A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).
Synonyms: (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamineInternational brands: Animex-OnRabeprazole
go.drugbank.com/drugs/DB01129ApprovedInvestigationalRabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. … Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.
Categories: Alimentary Tract and Metabolism, Antiinflammatory and Antirheumatic ProductsProducts: PARIET EISAI 10MG, RABEPRAZOL TAD 10MGAmphotericin B
go.drugbank.com/drugs/DB00681ApprovedInvestigationalby concentrations of amphotericin B ranging from 0.03 to 1.0 mcg/mL in vitro. … The antibiotic is without effect on bacteria, rickettsiae, and viruses.
Categories: Compounds used in a research, industrial, or household setting, Alimentary Tract and MetabolismProducts: AMPHOLIP ® 100MG/20ML, AMPHOLIP Injection 50mg/10ml