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Balsam of Peru
go.drugbank.com/drugs/DB11482ApprovedNutraceuticalVet approvedas safe (GRAS). … Balsam of Peru has also presented several allergens such as cinnamic acid, [DB06770] and [DB02130].
Benzatropine
go.drugbank.com/drugs/DB00245ApprovedInvestigationalwell as a decreased inhibition of serotonin and norepinephrine. … [A37914] Benztropine was developed by USL Pharma and officially approved by the FDA on 1996.[L5500]
Ripretinib
go.drugbank.com/drugs/DB14840ApprovedInvestigationalRipretinib, also known as Qinlock, is manufactured by Deciphera Pharmaceuticals and was initially approved by the FDA on May 15, 2020. … Ripretinib is a kinase inhibitor used for the treatment of advanced gastrointestinal stromal tumor (GIST) that has not adequately responded to other kinase inhibitors such as [sunitinib] and [imatinib]
ARCoV
go.drugbank.com/drugs/DB15855ExperimentalSARS-CoV-2 mRNA vaccine (ARCoV) is a novel mRNA coronavirus vaccine that consists of a lipid nanoparticle-encapsulated mRNA encoding the receptor binding domain of SARS-CoV-2[A220048]. … Preclinical studies in mice and non-human primates has shown that intramuscular administration of ARCoV elicited a Th1-biased cellular response and robust antibodies against SARS-CoV-2[A220048].
Ribose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001557TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Synonyms: PRIBisacodyl
go.drugbank.com/drugs/DB09020ApprovedInvestigational[A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300] … [A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM).
Synonyms: Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)Glycine
go.drugbank.com/drugs/DB00145ApprovedInvestigationalNutraceuticalVet approvedIt is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.
Mixtures: TRAVASOL® SOLUCION BAL 8.5% SIN ELECTROLITOSAmivantamab
go.drugbank.com/drugs/DB16695ApprovedInvestigationalnon-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertion mutations, as detected by an FDA-approved test, whose disease has progressed on or after platinum-based … [A235103,A235118] Amivantamab was found to be more effective than the EGFR inhibitor [erlotinib] or the MET inhibitor [crizotinib] _in vivo_.
Eugenol
go.drugbank.com/drugs/DB09086ApprovedInvestigationalEugenol is a naturally occurring phenolic molecule found in several plants such as cinnamon, clove, and bay leaves. … It has been used as a topical antiseptic as a counter-irritant and in dental preparations with zinc oxide for root canal sealing and pain control.
Cupric Chloride
go.drugbank.com/drugs/DB09131ApprovedCupric chloride, for injection, is a sterile, nonpyrogenic solution intended for use as an additive to solutions for Total Parenteral Nutrition (TPN).