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Ninerafaxstat

Ninerafaxstat is under investigation in clinical trial NCT07023614 (A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

MF-300

As a potential candidate for the treatment of sarcopenia, it has undergone phase 1 studies to evaluate safety, tolerability, and PK/PD characteristics.[A275368,L54983]

Ceperognastat

Ceperognastat is under investigation in clinical trial NCT05063539 (A Study of LY3372689 to Assess the Safety, Tolerability, and Efficacy in Participants With Alzheimer's Disease).

Neisseria meningitidis group W-135 capsular polysaccharide tetanus toxoid conjugate antigen

cryopreserved human liver cells

The Company's technology is centered on the isolation, expansion, and cryopreservation of liver cells (human hepatocytes) obtained from organ donor livers that are not suitable for whole organ transplantation

MDX-1303

MDX-1303 is a fully human antibody against the inhalation anthrax, the most lethal form of illness in humans caused by the Bacillus anthracis bacterium, and targets a protein component of these lethal … toxins known as the anthrax protective antigen.

CNS-5161

CNS 5161 is a blocker of the NMDA ion channel and has completed Phase IIa proof of concept clinical trials as a novel compound for the treatment of neuropathic pain.

Inositol 1,3-bisphosphate

The compound corresponds to the soluble headgroup of phosphatidylinositol 3-phosphate (PtdIns(3)P), an endosomal signaling lipid recognized by FYVE domains, and it has been used as a ligand in structural … Inositol 1,3-bisphosphate is a phosphorylated myo-inositol derivative and small molecule metabolite in which phosphate groups occupy the 1 and 3 positions of the inositol ring.

Deoxyribonuclease I

Because of the hypothesis that increased concentrations of high-molecular-weight DNA is a factor for airway obstruction, abnormal viscoelastic properties of the sputum, and recurrent exacerbations of respiratory … symptoms requiring parenteral antibiotics, aerosolized human DNase I has been administered to patients with cystic fibrosis[A227723].

Virus Specific T-Cell

These T-cells are then isolated from the donor and expanded in a culture to generate more VSTs. … Antigens identified as an immune target are presented by antigen-presenting cells (APCs) to T-cells along with other molecules that stimulate their growth and activation.