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Toralizumab
go.drugbank.com/drugs/DB16384InvestigationalToralizumab is under investigation in clinical trial NCT03605927 (CD40-L Blockade for Prevention of Acute Graft-versus-host Disease).
GI heptapeptide
go.drugbank.com/drugs/DB15070InvestigationalGI heptapeptide is under investigation in clinical trial NCT01391208 (Esophageal Protocol for Detection of Neoplasia in the Digestive Tract).
COVID-19 Nucleocapsid-GM-CSF Protein Lactated Ringer's Injection
go.drugbank.com/drugs/DB15845ExperimentalAs of July 2020, Medicine Invention Design, Inc. is sponsoring a small, controlled clinical trial for the COVID-19 AP TP Vaccine for ‘proof of concept.’
Stannsoporfin
go.drugbank.com/drugs/DB04912InvestigationalStannsoporfin is a competitive heme oxygenase (HO) inhibitor being developed by InfaCare, a subsidiary of WellSpring Pharmaceuticals, for the prevention of hyperbilirubinemia in infants at risk of developing
Bencyclane
go.drugbank.com/drugs/DB13488ExperimentalIts mechanism may involve block of calcium channels.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesCrenolanib
go.drugbank.com/drugs/DB11832InvestigationalCrenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
Categories: Receptor, Platelet-Derived Growth Factor alpha, antagonists & inhibitors, Receptor, Platelet-Derived Growth Factor beta, antagonists & inhibitorsBRG01
go.drugbank.com/drugs/DB18173InvestigationalBRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of nasopharyngeal carcinoma.[L48111]
CTR-107
go.drugbank.com/drugs/DB18583ExperimentalIt is being investigated for the treatment of familial exudative vitreoretinopathy.
Elebsiran
go.drugbank.com/drugs/DB19018InvestigationalElebsiran is under investigation in clinical trial NCT05461170 (SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.).
Olorofim
go.drugbank.com/drugs/DB15245InvestigationalOlorofim is under investigation in clinical trial NCT03340597 (Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects).
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Substrates