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Clevidipine
go.drugbank.com/drugs/DB04920ApprovedInvestigationalClevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: Cleviprex 0,5 mg/ml Emulsion zur InjektionStachyose
go.drugbank.com/drugs/DB19276ExperimentalSynonyms: Gal(.alpha.1->6)gal(.alpha.1->6)glc(.alpha.1->2.beta.)fru, -d-glucopyranoside, .beta.-d-fructofuranosyl o-.alpha.-d-galactopyranosyl-(1->6)-o-.alpha.-d-galactopyranosyl-(1->6)-Chloral hydrate
go.drugbank.com/drugs/DB01563ApprovedIllicitInvestigationalVet approvedA hypnotic and sedative used in the treatment of insomnia. … The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments.
Products: PMS-CHLORAL HYDRATE SYRUP 500 mg/5 ml, PMS-chloral Hydrate Syrup 100mg/mlBifikafusp alfa
go.drugbank.com/drugs/DB19185InvestigationalBifikafusp alfa is under investigation in clinical trial NCT05329792 (L19IL2/L19TNF in Skin Cancer Patients).
Synonyms: Immunoglobulin, anti-(human fibronectin ed-b domain) (synthetic human clone l19 scfv fragment) fusion protein with human interleukin 2Nivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] Nivolumab was granted FDA approval on 22 December 2014.[L12129] It is also available in combination with [relatlimab] under the brand name Opdualag.[L41265,L49996,L50001]
Mixtures: OPDUALAG® SOLUCION INYECTABLECategories: Immunoglobulin G, PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitorsBlack widow spider antivenin (equine)
go.drugbank.com/drugs/DB14113ApprovedBlack widow spider (_Latrodectus mactans_) antivenin is a treatment for black widow spider bites derived from the serum of healthy horses immunized against black widow spider venom.[L12792]
Synonyms: LATRODECTUS IMMUNE F(AB)2Cloxazolam
go.drugbank.com/drugs/DB01553ExperimentalThe usual dose of cloxazolam in adults is 3-12mg/day for anti-anxiety. … Cloxazolam is a benzodiazepine with anxiolytic, sedative/hypnotic, muscle relaxant, and antiepileptic effects.
Categories: Heterocyclic Compounds, 2-RingProducts: OLCADIL ® 2 MG COMPRIMIDOS, OLCADIL ® 4 MG COMPRIMIDOSRuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigationalRuxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: JAKAVI 5 MG (TABLETS), JAKAVI 5 MG TABLET, 14 ADETZofenopril
go.drugbank.com/drugs/DB13166ApprovedInvestigationalZofenopril is employed as both a cardioprotective and anti-hypertensive agent. It is an angiotensin-converting enzyme (ACE) inhibitor.
Mixtures: ZOPROTEC PLUS 30 MG/12.5 MG FILM KAPLI TABLET, 28 ADET, BIFRIL PLUS 30/12.5 MG FILM TABLET, 28 ADETProducts: BIFRIL 30 MG FILM TABLET, 28 ADET, ZOPROTEC 30 MG FILM KAPLI TABLET, 28 ADETFinerenone
go.drugbank.com/drugs/DB16165ApprovedInvestigational[A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449] … Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: KERENDİA 20 MG FİLM KAPLI TABLET, 28 ADET, KERENDİA 20 MG FİLM KAPLI TABLET, 98 ADET