Zofenopril

DB13166ApprovedInvestigationalSmall molecule

Zofenopril is an ACE inhibitor indicated in the treatment of hypertension. Zofenopril is employed as both a cardioprotective and anti-hypertensive agent.

Chemical structure of Zofenopril
Mechanism
Curator reviewed
Formula / weight
C22H23NO4S2 · 429.55 g/mol (avg)
Also known as
Zofenil

Resolves to

Compound
UNII290ZY759PICAS81872-10-8ChEMBLCHEMBL331378ChEBI78539PubChem92400KEGGD08688
Clinical / RWD
RxNorm39990ATCC09AA15ATCC09BA15ATCC09BX07
Structure
InChIKeyIAIDUHCBNLFXEF-MNEFBYGVSA-NSMILESC[C@H](CSC(=O)C1=CC=CC=C1)C(=O)N1C[C@H](C[C@H]1C(O)=O)SC1=CC=CC=C1
Targets
P12821ACE

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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849Drug interactionsStructured to mechanism, not free text
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4Clinical trialsPhase, status and sponsor resolved per trial
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3Structured indicationsCondition, population, route and combination as fields, not prose
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9ContraindicationsEach with its own population and attribute set
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182Marketed productsAcross 7 countries and 12 labellers
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3ATC codesIncluding every combination product, plus 13 drug categories
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6+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Zofenopril, and which of those have an active Phase 3 trial?

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