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Displaying results 6421 - 6430 of 10000 in total
  1. Drug

    LSZ-102

    go.drugbank.com/drugs/DB15362
    Investigational

    LSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).

  2. Drug

    Trametes versicolor fruiting body

    go.drugbank.com/drugs/DB14287
    Investigational

    Trametes versicolor fruiting body is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  3. Drug

    Ovemotide

    go.drugbank.com/drugs/DB19156
    Investigational

    Ovemotide is under investigation in clinical trial NCT00357461 (Ipilimumab With or Without Vaccine Therapy in Treating Patients With Previously Treated Stage IV Melanoma).

    Synonyms: L-valine, l-tyrosyl-l-leucyl-l-.alpha.-glutamyl-l-prolylglycyl-l-prolyl-l-valyl-l-threonyl-, (264-l-valine)melanocyte protein pmel 17 (human melanoma-associated me20 antigen)-(256-264)-peptide
  4. Drug

    SOBI-003

    go.drugbank.com/drugs/DB15451
    Investigational

    It is under investigation in clinical trial NCT03811028 (A Study to Assess the Safety, Tolerability, and Efficacy of Long-term SOBI003 Treatment in Pediatric MPS IIIA Patients). … SOBI-003 is a chemically modified variant of a recombinant human sulfamidase.

  5. Drug

    Omapatrilat

    go.drugbank.com/drugs/DB00886
    Experimental

    Omapatrilat is an investigational drug that inhibits both neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE). … The inhibition of NEP elevates natriuretic peptide levels, increasing excretion of sodium in urine, dilating blood vessels, and reducing preload and ventricular remodeling.

  6. Drug

    Radequinil

    go.drugbank.com/drugs/DB19722
    Investigational

    Radequinil is a small molecule drug. The usage of the INN stem '-nil' in the name indicates that Radequinil is a benzodiazepine receptor antagonist/agonist. … Radequinil is under investigation in clinical trial NCT00359944 (Safety and Efficacy Study of AC-3933 in Adults With Mild to Moderate Alzheimer's Disease).

  7. Drug

    Dihydrostreptomycin

    go.drugbank.com/drugs/DB11512
    ApprovedVet approvedWithdrawn

    Dihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity.

    Synonyms: N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl)-a-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-α-L-glucopyranosyl]-3-C-(hydroxymethyl)-α-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
  8. Drug

    Maduramicin

    go.drugbank.com/drugs/DB11525
    ExperimentalVet approved

    Maduramicin is an antiprotozoal agent used in veterinary medicine as prophylaxis against coccidiosis. … It is a naturally occurring compound which was first isolated from the actinomycete, Actinomadura rubra.

  9. Drug

    Utidelone

    go.drugbank.com/drugs/DB17575
    Investigational

    Utidelone (UTD1), a novel microtubule stabilizing agent, is an epothilone B analogue produced by genetic engineering.[A257544,A257549] It is under investigation in clinical trials for various cancers.

  10. Drug

    Efdoralprin alfa

    go.drugbank.com/drugs/DB18384
    Investigational

    Efdoralprin alfa is a recombinant human alpha-1 antitrypsin (AAT)-Fc fusion protein.[L54928] It is being investigated as a restorative therapy in adults with AATD emphysema.[L54928]