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Displaying results 6431 - 6440 of 10000 in total
  1. Drug

    Dubermatinib

    go.drugbank.com/drugs/DB15187
    Investigational

    Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL).

  2. Drug

    Wortmannin

    go.drugbank.com/drugs/DB08059
    Experimental

    Wortmannin is a steroid metabolite of _Penicillium funiculosum_ and _Talaromyces wortmannii_ fungi. This drug acts as a nonspecific, covalent inhibitor of phosphoinositide 3-kinase enzymes (PI3Ks).

  3. Drug

    Rebastinib

    go.drugbank.com/drugs/DB13005
    Investigational

    Rebastinib has been used in trials studying the treatment of Chronic Myeloid Leukemia. It is an inhibitor of Tie2 tyrosine kinase receptor and an antineoplastic agent.

  4. Drug

    Cyamemazine

    go.drugbank.com/drugs/DB09000
    Experimental

    Cyamemazine (Tercian), also known as cyamepromazine, is a typical antipsychotic drug of the phenothiazine class used primarily in the treatment of schizophrenia and psychosis-associated anxiety. … Cyamemazine actually behaves like an atypical antipsychotic, due to its potent anxiolytic effects (5-HT2C) and lack of extrapyramidal side effects (5-HT2A).

  5. Drug

    VPM4001

    go.drugbank.com/drugs/DB05089
    Experimental

    VPM4001 is an allogeneic vaccine for treatment of prostate carcinoma. … Interferon-γ enhances presentation of tumour antigens, whereas interleukin-2 stimulates T cells.

  6. Drug

    Alofanib

    go.drugbank.com/drugs/DB20918
    Investigational

    Alofanib is under investigation in clinical trial NCT04071184 (Study of Alofanib in Patients With Metastatic Gastric Cancer). Alofanib has a monoisotopic molecular weight of 413.07 Da. … The usage of the INN stem '-anib' in the name indicates that Alofanib is a angiogenesis inhibitor.

  7. Drug

    EHT899

    go.drugbank.com/drugs/DB05108
    Experimental

    EHT899 is a proprietary formulation of an HBV viral protein designed to eliminate the undesirable immune response elicited by the HBV infection.

  8. Drug

    Modimelanotide

    go.drugbank.com/drugs/DB15314
    Investigational

    Modimelanotide is under investigation in clinical trial NCT01897519 (A Safety and Efficacy Trial of Multiple Dosing Regimens of ABT-719 for the Prevention of Acute Kidney Injury in Subjects Undergoing

  9. Drug

    Pimelic Acid

    go.drugbank.com/drugs/DB01856
    Experimental

    A group of compounds that are derivatives of heptanedioic acid with the general formula R-C7H11O4. [PubChem]

  10. Drug

    PEP0101

    go.drugbank.com/drugs/DB18572
    Experimental

    PEP0101 is a nanocomplex consisting of elastin-like polypeptides and a small interfering RNA (siRNA) designed to down-regulate the expression of EVI1 oncogene in cancer cells.

    Synonyms: Nanocomplex consisting of a small interfering RNA that targets the human EV11 oncogenic transcription factor and an elastin-like polypeptide drug carrier.