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Displaying results 6431 - 6440 of 10000 in total
  1. Drug

    Hydroxocobalamin

    go.drugbank.com/drugs/DB00200
    ApprovedInvestigational

    Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is an injectable form of vitamin B 12 that has been used therapeutically to treat vitamin B 12 deficiency.

    Mixtures: TRIBEDOCE C/L, ENJEKSİYONLUK ÇÖZELTİ, 10 AMPUL (5+5)Categories: Heterocyclic Compounds with 4 or More Rings, Vitamin B Complex
  2. Drug

    Cloxazolam

    go.drugbank.com/drugs/DB01553
    Experimental

    The usual dose of cloxazolam in adults is 3-12mg/day for anti-anxiety. … Cloxazolam is a benzodiazepine with anxiolytic, sedative/hypnotic, muscle relaxant, and antiepileptic effects.

    Categories: Heterocyclic Compounds, 2-RingProducts: OLCADIL ® 2 MG COMPRIMIDOS, OLCADIL ® 4 MG COMPRIMIDOS
  3. Target

    3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2

    go.drugbank.com/bio_entities/BE0000059
    TargetEnzymeHumans

    3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. … The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids

    Polypeptides: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2Synonyms: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II, 3-beta-HSD II
  4. Drug

    Tenofovir alafenamide

    go.drugbank.com/drugs/DB09299
    ApprovedInvestigational

    [A178327] Tenofovir alafenamide is indicated to treat chronic hepatitis B,[L6241] treat HIV-1,[L4388,L6277,L6280,L6283] and prevent HIV-1 infections. … [A178219] It has been reported to produce a large antiviral efficacy at doses ten times lower than tenofovir disoproxil.

    Mixtures: ODEFSEY® 200 MG - 25 MG - 25 MG TABLETAS RECUBIERTAS, Descovy® (emtricitabine 200 mg/ tenofovir alafenamide 25 mg) film-coated tabletsCategories: Heterocyclic Compounds, 2-Ring, Vitamin B Complex
  5. Drug

    Izokibep

    go.drugbank.com/drugs/DB19081
    Investigational

    Izokibep is under investigation in clinical trial NCT05623345 (Psoriatic Arthritis Study of Izokibep).

    Synonyms: FUSION PROTEIN COMPOSED OF 3 BINDING DOMAINS CONSISTING OF THREE-ALPHA-HELIX MOTIFS, EACH DERIVED FROM THE IMMUNOGLOBULIN (IG)-BINDING Z-DOMAIN OF STAPHYLOCOCCAL PROTEIN A (SPA), ENGINEERED FOR BINDING
  6. Drug

    Aprepitant

    go.drugbank.com/drugs/DB00673
    ApprovedInvestigational

    Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. … Aprepitant, an antiemetic, is a substance P/neurokinin 1 (NK1) receptor antagonist which, in combination with other antiemetic agents, is indicated for the prevention of acute and delayed nausea and vomiting

    Mixtures: EMEND KAPSUL, 3 ADET, EMEND KAPSUL, 3 ADETCategories: Substance P/Neurokinin-1 Receptor Antagonist, Neurokinin 1 Antagonists
  7. Drug

    Hydrochlorothiazide

    go.drugbank.com/drugs/DB00999
    ApprovedInvestigationalVet approved

    [L7426,L7459] Hydrochlorothiazide was granted FDA approval on 12 February 1959.[L8444]

    Mixtures: CARDIK ® 3 160/5/12.5, CARDIK ® 3 160/5/12.5Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Ruxolitinib

    go.drugbank.com/drugs/DB08877
    ApprovedInvestigational

    Ruxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.

    Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: JAKAVI 5 MG (TABLETS), JAKAVI 5 MG TABLET, 14 ADET
  9. Drug

    Finerenone

    go.drugbank.com/drugs/DB16165
    ApprovedInvestigational

    [A236544,L34739] Finerenone was granted FDA approval on 9 July 2021,[L34739] followed by the EMA approval on 11 March 2022.[L41449] … Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart

    Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesProducts: KERENDİA 20 MG FİLM KAPLI TABLET, 28 ADET, KERENDİA 20 MG FİLM KAPLI TABLET, 98 ADET
  10. Drug

    Acheta domesticus

    go.drugbank.com/drugs/DB10866
    Approved

    House cricket allergenic extract is used in allergenic testing.

    Synonyms: Acheta domesticus