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AX200
go.drugbank.com/drugs/DB05093InvestigationalThe expression of the endogenous AX200 protein in the brain is increased after brain damage. … through the induction of neuro- and arteriogenesis and supporting the reorganisation of the nervous system.
Tepoxalin
go.drugbank.com/drugs/DB11466ExperimentalVet approvedTepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. … It is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such as hip dysplasia and arthritis.
SIG-007
go.drugbank.com/drugs/DB17710ExperimentalDeveloped by Sigilon Therapeutics, t is being investigated for the treatment of Fabry Disease.[L46153] … SIG-007 is a gene therapy that consists of cells that are genetically modified with a non-viral vector to express human alpha-galactosidase A.
Hu-rhEGF-rP64k/Mont
go.drugbank.com/drugs/DB15781Investigationalfor the treatment of advanced non-small cell lung cancer (NSCLC). … Hu-rhEGF-rP64k/Mont is a therapeutic vaccine composed by an antigen (recombinant human EGF (rhEGF) chemically conjugated to recombinant P64K (rP64K)) and an adjuvant (Montanide ISA51VG) being investigated
Escin
go.drugbank.com/drugs/DB15907InvestigationalSodium aescinate is under investigation in clinical trials for its potential to treat cerebral conditions, including NCT04247659 (studying the relationship between asymmetric vascular sign of cortex and
ARG201
go.drugbank.com/drugs/DB06621ExperimentalARG201, a bovine-derived Type I collagen, aims to induce immune tolerance in patients with Diffuse Systemic Scleroderma (dcSSc). … This drug was investigated in the completed clinical trial NCT0000567 (Multicenter Phase II Trial of Oral Type I Bovine Collagen in Scleroderma)
Surabgene lomparvovec
go.drugbank.com/drugs/DB21780InvestigationalSurabgene Lomparvovec is under investigation in clinical trial NCT07007065 (Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity
VX-702
go.drugbank.com/drugs/DB05470InvestigationalIn the future, VX-702 may be investigated for combination with methotrexate, a commonly used therapy for RA.
Dimethylthiambutene
go.drugbank.com/drugs/DB01444ExperimentalIllicitIt is now under international control under Schedule I of the UN Single Convention On Narcotic Drugs 1961, presumably due to high abuse potential, although little more information is available.
Vemtoberant
go.drugbank.com/drugs/DB21607InvestigationalVemtoberant is under investigation in clinical trial NCT05139615 (A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With