Tepoxalin

DB11466ExperimentalVet approvedSmall molecule

Tepoxalin is a nonsteroidal anti-inflammatory drug approved for veterinary use in the United States and many other countries. It is primarily used to reduce inflammation and relief of pain caused...

Mechanism: Pharmacologically active on Prostaglandin G/H synthase 2
Curator reviewed
Formula / weight: C₂₀H₂₀ClN₃O₃ · 385.85 g/mol (avg)
Code names: ORF-20485 · RWJ-20485

Resolves to

Compound

UNIITZ4OX61974CAS103475-41-8ChEMBLCHEMBL316040ChEBI76277KEGGD06075

Structure

InChIKeyXYKWNRUXCOIMFZ-UHFFFAOYSA-NSMILESCOC1=CC=C(C=C1)N1N=C(CCC(=O)N(C)O)C=C1C1=CC=C(Cl)C=C1

Targets

Q8SPQ9Prostaglandin G/H synthase 2P09917ALOX5P05112IL4

What you can answer from here — as of June 15, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1,663Drug interactionsStructured to mechanism, not free text

34+ReferencesStructured and connected to the statements they support

Which drugs share a target with Tepoxalin, and which of those have an active Phase 3 trial?

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