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Hydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalStructurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. … [A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984.[L5795]
Categories: Heterocyclic Compounds with 4 or More RingsProducts: HYDROMORPHON HCL PUR 16MG, HYDROMORPHON HCL PUR 24MGDeflazacort
go.drugbank.com/drugs/DB11921ApprovedDeflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD). … [L6694] Duchenne Muscular Dystrophy is an inherited disorder resulting from mutations of the dystrophin gene, which is important for muscle function.
Categories: Corticosteroids for Systemic Use, Corticosteroids for Systemic Use, PlainProducts: DEFLAZACORT EGRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. … However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.
Categories: Factor Xa Inhibitors, Direct factor Xa inhibitorsProducts: Pro-rivaroxaban, RIVAROXABAN EGFluoxetine
go.drugbank.com/drugs/DB00472ApprovedInvestigationalVet approved[A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).
Categories: Antidepressive Agents Indicated for DepressionSynonyms: (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamine, (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamineDaptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231384] Early work on developing daptomycin was abandoned due to observed myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a once-daily dosing … Daptomycin is a cyclic lipopeptide antibacterial agent with a broad spectrum of activity against Gram-positive bacteria, including methicillin-susceptible and -resistant _Staphylococcus aureus_ (MSSA/MRSA
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Daptomycin in Sodium Chloride, BEDAPT 500mg (Daptomycin for Injection 500mg per vial)Cefadroxil
go.drugbank.com/drugs/DB01140ApprovedInvestigationalVet approvedWithdrawnLong-acting, broad-spectrum, water-soluble, cephalexin derivative.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Pro-cefadroxil - 500, CEFADROXIL 1A PHARMA1000MGTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigationalIn 2004, topiramate was approved for the prevention of migraine in adults. … [A188309,L10544,L43478] Since 2012, the extended-release formulation has been approved in combination with [phentermine] for chronic weight management therapy in adults.
Products: Pro-topiramate, TOPIRAMATO EGFluvoxamine
go.drugbank.com/drugs/DB00176ApprovedInvestigationalFluvoxamine is an antidepressant which functions pharmacologically as a selective serotonin reuptake inhibitor. … Fluvoxamine has been in use in clinical practice since 1983 and has a clinical trial database comprised of approximately 35,000 patients.
Categories: Antidepressive Agents Indicated for DepressionProducts: FLUVOXAMINA EG, Gen-fluvoxamine 50mgSunflower oil
go.drugbank.com/drugs/DB14329InvestigationalSunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: OrgaPlus Super Care Balm for combination and oi ly skin type 20g, OrgaPlus Super Care Balm for combination and oi ly skin type 14gBrimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease. … [A179002] Brimonidine displays a higher selectivity toward the alpha-2 adrenergic receptors than [clonidine] or [apraclonidine], which are also alpha-2 adrenergic agonists.
Mixtures: Tim-Brim-Dor-Lat, Brim-Dor PFCategories: Sympathomimetics in Glaucoma Therapy