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Displaying results 641 - 650 of 10000 in total
  1. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384] … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.

    Synonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-prolineMixtures: LISINOPRIL IDROCLOROTIAZIDE EG, LISINOPRIL IDROCLOROTIAZIDE EG
  2. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Atenolol itself was developed early on in this history by Alvogen Malta under the trade name Tenormin and received FDA approval in September, 1981. … [A235860,A235865] A meta-analysis of over 145,000 patients showed the risk of stroke in patients taking atenolol may depend on the age of the patient.

    Mixtures: ATENOLOLO CLORTALIDONE EG, ATENOLOLO CLORTALIDONE EGProducts: ATENOLOLO EG
  3. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    FDA approved on July 1, 2011. … Rivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary.

    Products: RIVAROXABAN EG, RIVAROXABAN EG STADA
  4. Drug

    Sitagliptin

    go.drugbank.com/drugs/DB01261
    ApprovedInvestigational

    Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256 … The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar[FDA label,A2255].

    Mixtures: SITAGLIPTIN E METFORMINA GALENICUM, SITAGLIPTIN E METFORMINA GALENICUMCategories: Drugs Used in Diabetes
  5. Drug

    Captopril

    go.drugbank.com/drugs/DB01197
    ApprovedInvestigational

    Captopril may be used in the treatment of hypertension.

    Mixtures: CAPTOPRIL E IDROCLOROTIAZIDE HEXAL, CAPTOPRIL E IDROCLOROTIAZIDE SANDOZCategories: Agents Acting on the Renin-Angiotensin System
  6. Drug

    Azithromycin

    go.drugbank.com/drugs/DB00207
    ApprovedInvestigational

    It was initially approved by the FDA in 1991 [A174175]. … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].

    Products: AZITROMICINA EG, AZITROMICINA EG STADA
  7. Drug

    Ferrous cation

    go.drugbank.com/drugs/DB14510
    Investigational

    Products: FERRO GLUCONATO EG, RULOFER N
  8. Drug

    Xylometazoline

    go.drugbank.com/drugs/DB06694
    Approved

    Xylometazoline is an imidazoline derivative [A228523] with sympathomimetic and nasal decongestant activity. … In some countries, it is available as combination products with [ipratropium], [domiphen], or [dexpanthenol].

    Products: XILOMETAZOLINA EG, IMIDIN N NASENSPRAY
  9. Drug

    Loperamide

    go.drugbank.com/drugs/DB00836
    ApprovedInvestigational

    Loperamide is an anti-diarrheal agent that is available as an over-the-counter product for treating diarrhea.[L42785] The drug was first synthesized in 1969 and used medically in 1976. … [A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss.

    Mixtures: Meds on the Go, Doc in the Box All Day SupplyProducts: LOPERAMIDE EG, IMODIUM N
  10. Target

    ATP synthase F(1) complex subunit delta, mitochondrial

    go.drugbank.com/bio_entities/BE0000484
    TargetEnzymeHumans

    ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated

    Polypeptides: ATP synthase F(1) complex subunit delta, mitochondrial