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Cediranib
go.drugbank.com/drugs/DB04849InvestigationalThe novel indole-ether quinazoline Cediranib is a highly potent (IC50 < 1 nmol/L) ATP-competitive inhibitor of recombinant KDR tyrosine kinase in vitro. It is being developed clinically as a once-daily oral therapy for the treatment o...
Pumactant
go.drugbank.com/drugs/DB04955ExperimentalPumactant is a synthetic surfactant used for treating respiratory distress syndrome in neonates. It is a unique formulation of the naturally occurring phospholipids Dipalmitoylphosphatidycholine (DPPC) and Phosphatidyl Glycerol (PG).
MPT0B640
go.drugbank.com/drugs/DB16512InvestigationalMPT0B640 was under investigation in clinical trials NCT04526717 for COVID-19 infection and NCT04294875 for locally advanced or metastatic solid malignancies.
Plosaracetam
go.drugbank.com/drugs/DB21594InvestigationalPlosaracetam is under investigation in clinical trial NCT05199142 (A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SDI-118 in Elderly Male and Female Study Participants With Cognitive
Icalcaprant
go.drugbank.com/drugs/DB21651InvestigationalIcalcaprant is under investigation in clinical trial NCT06696755 (A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder
GEM-231
go.drugbank.com/drugs/DB05798InvestigationalMonoclonal antibodies are made in the laboratory and can locate and bind to cancer cells.
Sparteine
go.drugbank.com/drugs/DB06727ApprovedWithdrawnIt is a sodium channel blocker, so it falls in the category of class 1a antiarrhythmic agents.
Bafilomycin A1
go.drugbank.com/drugs/DB06733ExperimentalThe bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus.
Octacosanol
go.drugbank.com/drugs/DB11220InvestigationalNutraceuticalThis high–molecular-weight organic compound is the main component of a natural product wax extracted from plants [A27245]. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory