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Corticorelin
go.drugbank.com/drugs/DB05394InvestigationalIt is a type of neurohormone, also called hCRF. … It is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory.
Succinobucol
go.drugbank.com/drugs/DB05399InvestigationalAGI-1067, is a novel small molecule with anti-oxidant and anti-inflammatory properties that was discovered by AtheroGenics and designed to treat atherosclerosis of the blood vessels of the heart, or coronary
NAV 1800
go.drugbank.com/drugs/DB05437ExperimentalRIGScan CR49, a 125I-labelled CR monoclonal antibody directed against the tumour-associated antigen TAG-72, is undergoing development with Neoprobe for the intraoperative detection of metastatic colorectal
Etiprednol dicloacetate
go.drugbank.com/drugs/DB05442InvestigationalEtiprednol dicloacetate (BNP-166) is a soft corticosteroid with anti-inflammatory properties that has been indicated in the treatment of asthma and Chron's disease.
Smilagenin
go.drugbank.com/drugs/DB05450InvestigationalP58 therefore provides a totally novel mode of action with potential importance for diseases associated with ageing of the brain. … Smilagenin is a novel non-peptide, orally bioavailable neurotrophic factor inducer that readily reverses free radical neurotoxicity produced by 1-ethyl-4- phenylpyridium (MPP+) in dopaminergic neurones
KW-7158
go.drugbank.com/drugs/DB05498ExperimentalKW-7158 is a tricyclic compound with a non-cholingergic mechanism of action for the treatment of "urinary urgency," "frequent urination" and "urinary incontinence" associated with bladder overactivity … The therapeutic effects of KW-7158 in overactive bladder may be due to the activation of A-type K(+) channels which regulate afferent neuron excitability and firing properties in the dorsal root ganglion
Enokizumab
go.drugbank.com/drugs/DB05555InvestigationalA humanized immunoglobulin G1k anti-interleukin-9 mAb.
Teverelix
go.drugbank.com/drugs/DB05624InvestigationalA synthetic decapeptide, water-soluble Gonadotropin-releasing hormone antagonist. It has reached phase II clinical trials.
OP-145
go.drugbank.com/drugs/DB05672ExperimentalOP-145 is a synthetic antimicrobial peptide developed from human cathelicidin LL-37.
FX06
go.drugbank.com/drugs/DB05685InvestigationalFX06 is a naturally occurring peptide derived from the neo-N-terminus of fibrin (Bbeta(15-42)). It prevents leukocyte migration through the gap junctions of endothelial cells.