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Atazanavir
go.drugbank.com/drugs/DB01072ApprovedInvestigationalFood and Drug Administration (FDA) approved atazanavir on June 20, 2003.
Mixtures: ANCEF ® R, ANCEF ® RCategories: P-glycoprotein inducers, P-glycoprotein inhibitorsMaprotiline
go.drugbank.com/drugs/DB00934ApprovedMaprotiline is a tetracyclic antidepressant with similar pharmacological properties to tricyclic antidepressants (TCAs).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: LUDIOMIL 25 MG TABLET, 30 ADET, MAPROTIL 25 MG TABLET, 30 ADETEnfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalEnfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake … The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesProducts: FUZEON POLVO SOLUCION INYECTABLE 90 MG/MITolvaptan
go.drugbank.com/drugs/DB06212ApprovedInvestigationalTolvaptan is used to treat low blood sodium levels (hyponatremia) associated with various conditions like congestive heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormones (SIADH). FDA approved on May 19, 2009.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: Jidren 45 mg Tablet, 28 ADET, JİNARC 30 MG TABLET, 28 ADETBotaretigene sparoparvovec
go.drugbank.com/drugs/DB16814InvestigationalSynonyms: ADENO-ASSOCIATED VIRUS 2 INVERTED TERMINAL REPEAT FL, DNA (RECOMBINANT PSEUDOTYPED ADENO-ASSOCIATED VIRUS 5 VECTOR AAV-RPGR HUMAN RHODOPSIN KINASE PROMOTER FRAGMENT-REGULATED HUMAN RETINITIS PIGMENTOSA GTPASE REGULATOR RPGR-ORF15 ISOFORM GENE VARIANT PLUSBarth Syndrome
go.drugbank.com/conditions/DBCOND0000526Drugs: ElamipretideSynonyms: 3-Methylglutaconic aciduria type 2 (disorder)Stage 4 Pancreatic adenocarcinoma
go.drugbank.com/conditions/DBCOND0025282Drugs: GemcitabineSynonyms: Stage 4 Pancreatic adenocarcinomaMilnacipran
go.drugbank.com/drugs/DB04896ApprovedInvestigational(BACE-1), which has investigationally been associated with β-amyloid plaque formation - making the agent a possible course of treatment for Alzheimer's disease [A175957]. … Nevertheless, milnacipran demonstrates a somewhat unique characteristic among SNRIs to elicit a relatively balanced reuptake inhibition of both serotonin and noradrenaline, with a somewhat increased preference
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: IXEL 25 MG KAPSUL, 28 ADET, Ixel 25 mg - KapselnUlipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalA recent systematic review proclaimed that the majority of available evidence demonstrates an inhibitory effect on ovulation rather than a post-fertilization effect on the endometrium, which has been heavily … It is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ESMYA® 5 MG COMPRIMIDOS, JOSEİ 30 MG TABLET, 1 ADETGemifloxacin
go.drugbank.com/drugs/DB01155ApprovedInvestigationalGemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-RingProducts: ONFACT 320 MG FİLM TABLET, 5 ADET, ONFACT 320 MG FİLM TABLET, 7 ADET